NCT Number: NCT07762937
This randomized controlled trial will investigate whether adding neurodynamic tensioning to a grip strengthening program provides additional improvements in hand grip strength in healthy adults. Sixty participants aged 18 to 40 years will be randomly assigned to two groups. Both groups will perform a standardized grip strengthening program for six weeks, three days per week. The experimental group will additionally receive neurodynamic tensioning exercises targeting the median and ulnar nerves. Hand grip strength will be assessed at baseline, week 3, and week 6. The study aims to determine whether neurodynamic tensioning provides additional benefit beyond grip strengthening alone.
Trial opening soon.
Get NotifiedThis study is designed as a prospective, two-arm, parallel-group randomized controlled trial investigating the additional effects of neurodynamic tensioning on hand grip strength in healthy adults. A total of 60 participants aged 18 to 40 years will be enrolled and randomly allocated in a 1:1 ratio to either a control group or an experimental group using computer-based block randomization.
Participants in both groups will perform a standardized grip strengthening program using an adjustable hand gripper for six weeks, three sessions per week. Each session will include three sets of 8-12 repetitions, with progressive resistance according to participant performance and perceived exertion.
In addition to the same grip strengthening program, participants in the experimental group will receive neurodynamic tensioning targeting the median and ulnar nerves. Neurodynamic techniques will be performed within pain-free limits using controlled tensioning movements. For each nerve, three sets of 10 repetitions will be performed before the grip strengthening exercises.
The primary outcome will be hand grip strength, measured using a Jamar hand dynamometer or an equivalent valid and reliable hand dynamometer. Grip strength will be assessed in standardized and different upper-extremity positions. Secondary outcomes will include pinch strength, manual dexterity, perceived exertion, intervention adherence, and adverse events.
Assessments will be performed at baseline (T0), week 3 (T1), and week 6 (T2). The outcome assessor will be blinded to group allocation. The main analysis will evaluate group, time, and group-by-time interaction effects to determine whether adding neurodynamic tensioning to grip strengthening results in greater improvement in hand grip strength than grip strengthening alone.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants will perform a standardized grip strengthening program using an adjustable hand gripper with the dominant hand for six weeks, three sessions per week. Each session will consist of 3 sets of 8-12 repetitions, with approximately 2 seconds of gripping and 2 seconds of relaxation per repetition. Rest periods of 60-90 seconds will be provided between sets. Resistance will be progressively adjusted according to performance and perceived exertion.
Neurodynamic tensioning targeting the median and ulnar nerves will be applied before the grip strengthening program. For each nerve, 3 sets of 10 repetitions will be performed, with each repetition consisting of approximately 4-5 seconds of controlled rhythmic tensioning. A 30-second rest period will be provided between sets. The technique will be performed within pain-free limits, producing only a mild stretching sensation.
Time frame: Baseline, Week 3, and Week 6
Hand grip strength of the dominant hand will be measured in kilograms (kg) using a Jamar hand dynamometer or an equivalent valid and reliable hand dynamometer. Measurements will be performed in three upper-extremity positions: standard seated position with the elbow at 90 degrees of flexion, elbow extension with the shoulder in a neutral position, and shoulder at 90 degrees of flexion with the elbow extended. Three trials will be performed in each position, and the mean of the three measurements will be used for analysis.
Time frame: Baseline, Week 3, and Week 6
Pinch strength will be assessed using a pinch gauge, if available, including lateral and/or palmar pinch measurements. Measurements will be performed on the dominant hand, and changes over time will be compared between groups.
Time frame: Baseline, Week 3, and Week 6
Manual dexterity will be assessed using the Nine-Hole Peg Test or an equivalent valid and reliable manual dexterity test. Performance will be recorded at each assessment time point, and changes over time will be compared between groups.
Time frame: Baseline, Week 3, and Week 6
Perceived exertion during the grip strengthening exercises will be recorded using a rating of perceived exertion (RPE). RPE will be used to monitor exercise intensity and guide progression of resistance throughout the intervention.
Contact information is provided by the study sponsor or research team.
Tokat Gaziosmanpasa University
Other
Effect of Neurodynamic Tensioning Added to a Grip Strengthening Program on Hand Grip Strength: A Randomized Controlled Trial
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07586085
Hand, Ice Hockey
Falun, Dalarna County, Sweden
View Trial DetailsNCT07586033
Athletic Injuries, Cumulative Trauma Disorders
View Trial DetailsNCT07522060
Arm Injuries, Arthritis
Ankara, Turkey (Türkiye)
View Trial DetailsNCT07235449
Hand
Istanbul, Turkey (Türkiye)
View Trial Details