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NCT Number: NCT07761949

Assessing the Impact of Streetscape Exposure on Children's Perception

The primary objective is to determine how streetscape exposure influences children's visual perception and psychological perception. The secondary aim is to identify streetscape elements associated with both visual and psychological perception, thereby providing evidence for environmental interventions in urban planning and public health.

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Key information

Age range

6 year–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China

Location status: Recruiting

Location contact

Institutional Review Board/Ethics Committee of the Sun Yat-sen

CONTACT

[email protected]

+86-20-87330341

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1: Myopia group: (1) informed consent obtained; (2) children aged 6-18 years; (3) no contraindications for wearing the eye-tracker (e.g., high astigmatism, head/neck injury); (4) myopia already present in at least one eye (spherical equivalent ≤ -0.50 D).

2: Emmetropia group: (1) informed consent obtained; (2) children aged 6-18 years; (3) no contraindications for wearing the eye-tracker (e.g., high astigmatism, head/neck injury).

Exclusion criteria

  • 1: Myopia group: (1) high myopia in either eye (spherical equivalent ≤ -6.00 D); (2) any ocular pathology other than myopia (strabismus, amblyopia, congenital cataract, juvenile glaucoma, retinal disease, etc.); (3) systemic disorders that may affect vision or visual development (e.g., diabetes); (4) anisometropia > 1.00 D or astigmatism > 2.00 D in either eye.

2: Emmetropia group: (1) myopia or hyperopia in either eye (spherical equivalent ≤ -0.50 D or ≥ +0.50 D); (2) any ocular pathology (strabismus, amblyopia, congenital cataract, juvenile glaucoma, retinal disease, etc.); (3) systemic disorders that may affect vision or visual development (e.g., diabetes); (4) anisometropia > 1.00 D or astigmatism > 2.00 D in either eye.

Treatment and study plan

Virtual simulation of street visual environment exposure

Other

Transforming real street scenes into virtual simulation environments, and recreating the visual exposure of actual street scenes in a laboratory setting through wearing VR headsets.

Primary outcomes

  1. Environmental defocus

    Time frame: First day

    The eye movement behaviors of the subjects were measured using the HTC VR helmet and the 7XINiwei aSee Studio, and then calculated by combining with the deep learning algorithm.

Secondary outcomes

  1. Perception evaluation

    Time frame: First day

    After the experiment process was completed, the Environmental Perception Questionnaire was used to measure the subjects' psychological perception of the streetscape environment, such as whether it was safe and comfortable. By comparing the pictures, the option that better matches the description is selected. The more times a picture is chosen, the safer or more comfortable it is considered.

Other outcomes

  1. Intensity of physical activity

    Time frame: First day

    Use the modified GPAQ physical activity questionnaires. Each question has 5 options, representing scores from 0 to 5. The arithmetic mean score of all the questions represents the activity level of the child.

  2. Axis Length

    Time frame: First day

    Under natural pupils, axial length was measured with the IOL Master. One eye was occluded while the fellow eye fixated straight ahead; three readings were taken and averaged.

  3. Refractive demand at fixation

    Time frame: First day

    The eye movement behaviors of the subjects were measured using the HTC VR helmet and the 7XINiwei aSee Studio, and then calculated by combining with the deep learning algorithm.

  4. Visual acuity

    Time frame: First day

    Use the ETDRS visual acuity chart

  5. Non-cycloplegic refraction

    Time frame: First day

    Measure using an automatic optometry instrument. The refractive power measured in the non-ciliary muscle paralysis state is expressed by the equivalent spherical refraction (SER), where SER = spherical refractive power + 1/2 × cylindrical refractive power. Computer refraction operation standard: Each eye is measured continuously 3 times, and the average value automatically output by the instrument is taken as the final result.

Sponsors and collaborators

Lead sponsor

Zhongshan Ophthalmic Center, Sun Yat-sen University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Aug 13, 2026
Registry last updated
Aug 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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