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Completed

NCT Number: NCT07756866

A Clinical Trial to Evaluate the Effects of Cowboy Colostrum on Gut Health, Body Composition, Hair Growth, and Skin Appearance

This study evaluates the effects of Cowboy Colostrum bovine colostrum powder on gut health, body composition, hair growth, and skin appearance in generally healthy adults aged 21-47 with concerns in these areas. The trial is a single-arm, unblinded, virtual study conducted over 12 weeks in 35 participants who will use the test product daily.

Participants will complete questionnaires and provide weight and waist circumference measurements at Baseline, Week 4, Week 8, and Week 12. The primary focus is on changes in weight and waist circumference, while secondary outcomes include participants' perceptions of gastrointestinal health, physical activity, hair growth, skin appearance, and overall health and well-being.

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Key information

Conditions

Gut Health Body Composition Gastrointestinal Health Hair Growth Healthy Weight Management Skin Appearance

Age range

21 year–47 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Citruslabs

Las Vegas, Nevada, 89101, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be male or female
  • Be aged 21-47
  • Anyone with concerns regarding all of the following over the past four weeks: gut health, healthy weight management, hair growth, and skin appearance
  • BMI 25-33 kg/m²
  • Anyone who is generally healthy and does not live with any uncontrolled chronic disease
  • Anyone who is physically active at least once per week
  • If taking any products, herbal remedies, over-the-counter medications, or supplements that target weight, gut health, physical activity, hair growth, or skin appearance, has been doing so consistently for three months and is willing to maintain this routine for the study duration
  • Willing to maintain their current diet and sleep schedule for the duration of the study
  • Willing to use the same skincare routine and make-up products for at least one month prior to the study, and willing to maintain this routine for the duration of the study
  • Resides in the United States

Exclusion criteria

  • Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders
  • Anyone who has undergone any surgeries or invasive treatments in the last six months, or has any planned during the study period
  • Has had any major illness in the last three months
  • Anyone who has taken an antibiotic in the last three months
  • Anyone currently taking a weight loss medication, including but not limited to Wegovy, Mounjaro, and Ozempic
  • History of an autoimmune disorder, diabetes, or endocrine disorder
  • Food intolerances, allergies, or sensitivities such as dairy allergy and lactose intolerance
  • Has a known history of severe digestive disorders like acid reflux, Irritable Bowel Syndrome (IBS), Irritable Bowel Disease (IBD), Crohn's disease, or gastrointestinal tract surgeries
  • Anyone diagnosed with a skin or hair condition
  • Anyone who does not consume animal products for any reason
  • Currently undergoing hair treatment or using other hair growth/thickening products
  • Currently taking any prescription medication for hair loss
  • Anyone with any conditions that affect the hair or scalp (e.g., alopecia areata)
  • Anyone planning to undergo facial treatments during the study period, including Botox, dermal fillers, and chemical peels
  • Anyone with any allergies or sensitivities to any of the study product ingredients
  • Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period)
  • Heavy drinkers, defined as a woman who drinks 8 or more alcoholic drinks per week or a man who drinks 15 or more alcoholic drinks per week
  • Anyone unwilling to follow the study protocol
  • Anyone with a history of substance abuse
  • Anyone who is currently a smoker or has been a smoker in the past 3 months
  • Currently partaking in another research study or will be partaking in any other research study for the next 12 weeks or at any point during this study's duration

Treatment and study plan

Cowboy Colostrum

Dietary Supplement

All participants take two scoops of Cowboy Colostrum bovine colostrum powder daily (3.4 g serving containing 3 g bovine colostrum, organic Madagascar vanilla powder, monkfruit extract, and sea salt), either directly in the mouth or frothed into cold or warm liquids such as water, iced coffee, iced matcha, smoothies, yogurt, or oatmeal at any time of day for 12 weeks. The product must not be added to any liquid over 140 degrees.

Primary outcomes

  1. Change in Body Weight

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Self-reported body weight measured daily for three consecutive days at each time point using a Withings smart scale; the average of the two closest values is used

  2. Change in Waist Circumference

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Self-reported waist circumference measured using a tape measure

Secondary outcomes

  1. Change in Gastrointestinal Symptoms

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via the Gastrointestinal Symptoms Rating Scale (GSRS) self-report questionnaire

  2. Change in Digestion-associated Quality of Life

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via the Digestion-associated Quality of Life questionnaire (DQLQ) self-report questionnaire

  3. Change in Physical Activity

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via the Godin Leisure-Time Exercises Questionnaire (GLTE) self-report questionnaire

  4. Participants' Perception of Bloating

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  5. Participants' Perception of Bowel Movement Frequency

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  6. Participants' Perception of Digestion

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  7. Participants' Perception of Healthy Weight Management

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  8. Participants' Perception of Energy Levels

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  9. Participants' Perception of Hair Growth

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  10. Participants' Perception of Hair Texture

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  11. Participants' Perception of Skin Brightness

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  12. Participants' Perception of Skin Clearness

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

  13. Participants' Perception of Product Efficacy

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Assessed via self-report questionnaire item

Sponsors and collaborators

Lead sponsor

Cowboy Colostrum

Industry

Collaborators

  • Citruslabs

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Aug 11, 2026
Registry last updated
Aug 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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