Precure Targeted Accrual and Rapid Growth in Enrollment Trial Study

The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease advancement before it becomes serious or complex, and 4) identify potential targets for disease therapy.

Participants will be asked to:

* collect biological samples

Enrolling by invitation

Interested in participating?

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Key information

Conditions

Exposure, Environmental Disease Attributes Disease Susceptibility Genetic Predisposition Genetic Predisposition to Disease Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age ≥ 18 years
Registered Mayo Clinic patient
Able to provide informed consent

Exclusion criteria

Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study

Treatment and study plan

Primary outcomes

Number of participants (up to 100,000) who provide biospecimens and have associated environmental exposure and phenotypic data successfully linked and stored within the biorepository and research database for future research.

Time frame: Up to 5 years

Interested in participating?

Enrolling by invitation

Interested in participating?

Request Info

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Precure Targeted Accrual and Rapid Growth in Enrollment Trial (TARGET) Study

Acronym: TARGET

Important dates

Study start: 2026
Primary completion: 2030
Study completion: 2035
First posted: Aug 10, 2026
Registry last updated: Aug 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Enrolling by invitation