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NCT Number: NCT07755709

Ultrasound Scoring System for Diagnosis and Prediction of Severity and Surgical Outcomes of Placenta Accreta Spectrum

Primary Objective:

To determine the optimal cutoff values of the ultrasound score for different PAS subtypes (no PAS, placenta accreta, placenta increta, and placenta percreta). To evaluate the diagnostic accuracy of the novel Ultrasound Scoring System in predicting the severity of Placenta Accreta Spectrum (PAS) (placenta accreta, increta, and percreta).

Secondary Objective:

* To correlate the novel ultrasound score with intraoperative findings (considered the gold standard) during cesarean delivery, including the degree of placental invasion and the need for surgical interventions (hysterectomy, bladder repair). * To assess the relationship between the novel ultrasound score and postoperative complications, such as:

* Requirement for hysterectomy * Bladder or bowel injury * Blood transfusion requirement * ICU admission rates * To explore the potential for integrating the Ultrasound Scoring System with other clinical indicators (e.g., patient age, parity, and history of cesarean sections) to enhance the predictive accuracy for PAS.

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Key information

About this study

Primary Objective:

  • To determine the optimal cutoff values of the ultrasound score for different PAS subtypes (no PAS, placenta accreta, placenta increta, and placenta percreta).
  • To evaluate the diagnostic accuracy of the novel Ultrasound Scoring
  • System in predicting the severity of Placenta Accreta Spectrum (PAS) (placenta accreta, increta, and percreta).

Secondary Objective:

  • To correlate the novel ultrasound score with intraoperative findings (considered the gold standard) during cesarean delivery, including the degree of placental invasion and the need for surgical interventions (hysterectomy, bladder repair).
  • To assess the relationship between the novel ultrasound score and postoperative complications, such as:
  • Requirement for hysterectomy
  • Bladder or bowel injury
  • Blood transfusion requirement
  • ICU admission rates
  • To explore the potential for integrating the Ultrasound Scoring System with other clinical indicators (e.g., patient age, parity, and history of cesarean sections) to enhance the predictive accuracy for PAS.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant women aged 18 to 45 years.
  • Gestational age ≥28 weeks at the time of enrollment.
  • Diagnosed Placenta Previa with a history of:
  • One or more previous cesarean sections
  • Uterine scarring due to previous surgery as (myomectomy, D&C, Metroplasty).
  • Singleton pregnancy.

Exclusion criteria

  • Women with multiple pregnancies (twins, triplets, etc.).
  • Pregnancies complicated by acute medical conditions (e.g., heart failure, uncontrolled diabetes).
  • Prior history of Blood diseases. (other than those related to pregnancy).
  • Women who refuse to participate or withdraw consent during the study.

Treatment and study plan

Primary outcomes

  1. degree of placental invasion and inability to conserve the uterus

    Time frame: 1 week

    Need for Hysterectomy: Determined by the degree of placental invasion and inability to conserve the uterus &Histopathogy confirmation. Bladder Injury: Recorded if any injury occurs during the procedure.

    Blood Transfusion Requirement: Amount of blood transfused intraoperatively.

    ICU Admission: Postoperative ICU admission requirement due to hemorrhage or other complications.

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed Adel Khalifa, resident

CONTACT

[email protected]

01096679590

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

A Novel Ultrasound Scoring System for Diagnosis and Prediction of Severity and Surgical Outcomes of Placenta Accreta Spectrum

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Aug 10, 2026
Registry last updated
Aug 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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