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Enrolling by Invitation

NCT Number: NCT07754357

Ultrasound-Guided T2 Erector Spinae Plane Block Versus Intercostobrachial Block in AV Fistula Surgery.

This study aims to determine whether ultrasound guided ESP block at 2nd thoracic vertebrae is non inferior to ultrasound guided ICBN block as adjunct to supraclavicular brachial plexus block in achieving complete sensory blockade of the medial upper arm during AVF superficialization

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Key information

About this study

Arteriovenous fistula (AVF) superficialization is an essential procedure for patients with end-stage renal disease . The supraclavicular brachial plexus block is commonly used for upper extremity surgeries .Because the ICBN originates from the T2 nerve root below the C5-T1 nerve roots comprising the brachial plexus, brachial plexus blocks are ideally supplemented with an ICBN infiltration block for medial upper arm coverage.The ICBB requires precise ultrasound guidance to target the ICBN, which is small and variably located, making it technically challenging and time-intensive.

ESP block at T2 level can provide broad coverage, ease of Performance, superficial injection and requiring less technical expertise compared to the ICBB .

The patients are randomly allocated into 2 groups :

  • Erector spinae plane block group (Group ESP): will receive 10 ml of 0.5% bupivacaine injected into the erector spinae plane at T2 level under ultrasound guidance.
  • Intercostobrachial block group (Group ICBB): will receive 10 ml of 0.5% bupivacaine injected around intercostobrachial nerve under ultrasound guidance. • Standard Supraclavicular Brachial plexus Block will be performed for all patients using 20 ml of 0.5% bupivacaine under ultrasound guidance.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • Adults scheduled for upper extremity surgeries under regional anesthesia.
  • Age: 18-65 years.
  • American society of Anesthesiologists (ASA) III.
  • Body Mass Index (BMI) < 35 kg/m².

Exclusion criteria

  • •Allergy to local anesthetics.
  • Coagulopathy or infection at injection sites.
  • Pre-existing neuropathy or significant psychiatric disorders.
  • Pregnant or lactating women.

Treatment and study plan

Ultrasound Guided Intercostobrachial Nerve Block

Procedure
  • Position: patient supine with arm abducted.
  • Ultrasound setup: High frequency probe positioned at upper axillary region.
  • Technique: Needle will be advanced into subcutaneous tissue, in-plane to target intercostobrachial nerve near axillary artery.
  • Drug: 10 ml of 0.5% bupivacaine.

Other names: ICBB

Ultrasound Guided Erector Spinae Plane Block at T2 level

Procedure
  • Position: patient sitting or in lateral decubitus.
  • Ultrasound setup: High frequency linear transducer will be placed in a parasagittal 2-3 cm lateral to spinous process at T2 level, erector spinae muscles will be identified superficial to the tip of T2 transverse process, patient's skin anesthetized with 3 ml of 2 % lidocaine subcutaneously, the tip of the 22- gauge 80-mm block needle(Sonoplex, Pajunk Medical, Geisingen, Germany) needle will be placed into the facial plane on the deep (anterior) aspect of erector spinae muscle. location of needle tip will be confirmed by visible fluid spread lifting the erector spinae muscle off the bony shadow of the transverse process then 10 ml of 0.5% bupivacaine will be injected into the facial plane that will be confirmed by visible hydrodissection .

Primary outcomes

  1. Proportion of patients achieving complete sensory blockade during AVF superficialization

    Time frame: baseline then at 15,30,60,120 minutes intraoperative assessment for vital signs and sensory blockade

    No discomfort and no need for sedation or conversion to general anesthesia

Secondary outcomes

  1. Time to achieve complete sensory blockade.

    Time frame: Time for complete sensory blockade in minutes within 30 minutes

    How much time required to achieve complete sensory blockade in minutes

  2. Patient's satisfaction (assessed using Likert scale).

    Time frame: At the first 24 hours

    Patient satisfaction was evaluated using a five-point Likert scale (1 = very dissatisfied, 2 = dissatisfied, 3 = neutral, 4 = satisfied, and 5 = very satisfied)

  3. Total opioid consumption in 24 hours

    Time frame: in the first 24 hours

    Total opioid consumption in 24 hours postoperative in mg /kg

  4. The visual analog scale(VAS)

    Time frame: in the first 12 hours

    measure a patient pain intensty ,commonly used interpretation is 0:no pain,1-3 :mild pain.4-6:moderate pain,7-10 :sever pain

Sponsors and collaborators

Lead sponsor

Fatma Hatem Mokhtar

Other

Collaborators

  • Aswan University Hospital

Registry information

Official study title

Ultrasound-Guided T2 Erector Spinae Plane Block Versus Intercostobrachial Block as Adjunct to Supraclavicular Brachial Plexus Block in AV Fistula Surgery.

Acronym: ICBN/ESP

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 10, 2026
Registry last updated
Aug 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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