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NCT Number: NCT07750184

Immediate Effects of Kinesio Taping on Thoracic Outlet Syndrome

The goal of this clinical trial is to evaluate the immediate effects of Kinesio Taping compared with sham taping in adults with Thoracic Outlet Syndrome (TOS). The study aims to determine whether a single application of Kinesio Taping provides greater improvements in symptom severity, grip strength, and hand dexterity than sham taping. The main questions it aims to answer are:

Does a single application of Kinesio Taping reduce symptom severity and improve tolerance to the Roos test compared with sham taping? Does a single application of Kinesio Taping improve grip strength and hand dexterity compared with sham taping? Researchers will compare participants receiving Kinesio Taping with those receiving sham taping to determine whether the observed effects are attributable to the therapeutic application of Kinesio Taping rather than nonspecific or placebo effects.

Participants will:

* undergo baseline assessments of symptom severity during the Roos test, Roos test completion time, grip strength, and hand dexterity; * be randomly assigned to receive either Kinesio Taping or sham taping; * undergo immediate post-intervention assessments using the same outcome measures.

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Key information

Age range

20 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sivas Cumhuriyet University

Merkez, Sivas, 58140, Turkey (Türkiye)

About this study

Thoracic Outlet Syndrome (TOS) is a neurovascular entrapment disorder caused by compression of the brachial plexus and/or subclavian vessels at the thoracic outlet. Patients commonly experience pain, paresthesia, weakness, and reduced upper-extremity function, leading to impaired performance in daily activities. Conservative treatment is considered the first-line approach for most patients and typically includes postural correction, therapeutic exercise, manual therapy, and activity modification.

Kinesio Taping (KT) is a non-invasive intervention that has been widely used in musculoskeletal rehabilitation to reduce pain, enhance proprioception, and improve functional performance. Previous studies have reported beneficial effects of KT in several peripheral nerve-related conditions, including carpal tunnel syndrome, lateral epicondylitis with radial nerve involvement, and peripheral neuropathies. However, evidence regarding its effectiveness in patients with TOS remains limited.

To date, only one randomized controlled trial has investigated the effects of KT in patients with TOS, demonstrating improvements in pain, paresthesia, disability, and quality of life. Nevertheless, the immediate effects of KT on objective motor performance outcomes, particularly grip strength and hand dexterity, have not been investigated. Since these outcomes are essential determinants of upper-extremity function and directly influence activities of daily living, addressing this knowledge gap may provide clinically relevant evidence for rehabilitation practice.

This randomized, sham-controlled trial is designed to investigate the immediate effects of a single KT application on symptom severity, response to the Roos test, grip strength, and hand dexterity in patients with TOS. The findings are expected to clarify whether KT produces immediate functional benefits beyond placebo effects and to provide evidence for its role as an adjunctive intervention in the conservative management of TOS.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of Thoracic Outlet Syndrome (TOS) confirmed by a thoracic surgeon.
  • Presence of symptoms consistent with TOS.
  • Ability to understand the study procedures and provide written informed consent.

Exclusion criteria

  • History of fracture or surgery involving the cervical spine, shoulder, elbow, wrist, or hand that could affect upper-extremity function.
  • Neurological disorders affecting upper-extremity function (e.g., stroke, multiple sclerosis, peripheral neuropathy unrelated to TOS).
  • Other upper-extremity musculoskeletal disorders that may influence grip strength or hand dexterity (e.g., carpal tunnel syndrome, trigger finger, thumb carpometacarpal osteoarthritis).
  • Skin lesions, allergy to adhesive tape, or any dermatological condition preventing tape application.
  • Pregnancy.
  • Inability to perform the assessment procedures.

Treatment and study plan

Kinesio taping

Device

A single application of therapeutic Kinesio Taping will be performed according to a standardized protocol by an experienced physiotherapist.

sham taping- not therapeutic

Other

A single application of sham taping will be performed according to a standardized protocol by an experienced physiotherapist.

Primary outcomes

  1. Grip strength

    Time frame: Immediately before and immediately after the intervention

    Grip strength will be measured using a Jamar hydraulic hand dynamometer. The change from baseline to immediately after the intervention will be compared between groups.

Secondary outcomes

  1. Hand dexterity

    Time frame: Baseline and immediately after taping

    Hand dexterity will be assessed using the Minnesota Manual Dexterity Test. The change from baseline to immediately after the intervention will be compared between the Kinesio Taping and sham taping groups.

Other outcomes

  1. Roos test

    Time frame: baseline to immediately after the intervention

    The duration (seconds) participants are able to maintain the Roos test position before symptom limitation will be recorded. The change from baseline to immediately after the intervention will be compared between groups.

Study contacts

Contact information is provided by the study sponsor or research team.

FERAY KARADEMİR, PhD

CONTACT

[email protected]

+905053137582

Tüzün Fırat, PhD

CONTACT

[email protected]

+905053137582

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

Immediate Effects of Kinesio Taping on Symptoms, Grip Strength, and Hand Dexterity in Patients With Thoracic Outlet Syndrome

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 6, 2026
Registry last updated
Aug 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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