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NCT Number: NCT07747961

Effect of Virtual Reality Mediated Gamified Rehabilitation in Children With Spastic Diplegic Cerebral Palsy

This randomized controlled trial aimed to evaluate the effectiveness of a Virtual Reality (VR)-mediated gamified rehabilitation program compared with conventional physical therapy in children with spastic diplegic cerebral palsy. Forty-two children aged 7-15 years with Gross Motor Function Classification System (GMFCS) Levels II and III were recruited from Rafsan Neuro Rehab Center, Peshawar. Participants were randomly allocated into two equal groups. The intervention group received VR-based gamified rehabilitation using Xbox Kinect along with physiotherapy, while the control group received conventional physiotherapy only. Both groups completed 18 treatment sessions over six weeks. Outcome measures included the Timed Up and Go Test (TUG), Pediatric Balance Scale (PBS), Trunk Impairment Scale (TIS), and Gross Motor Function Classification System (GMFCS). The findings demonstrated that VR-mediated rehabilitation significantly improved functional mobility, balance, and trunk control compared with conventional therapy. The study concludes that VR-based rehabilitation is an effective, motivating, and clinically useful intervention for children with spastic diplegic cerebral palsy and may improve rehabilitation outcomes and functional independence.

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Key information

Age range

7 year–15 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ibadat International University

Islamabad, 47000, Pakistan

Location status: Recruiting

Location contact

Hafsah Arshad, PhD*

CONTACT

[email protected]

03315165234

Tazveena IIUI, MS (Paeds)

PRINCIPAL_INVESTIGATOR

About this study

Refer to complete thesis introduction, methodology and protocol.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with spastic diplegic cerebral palsy.
  • Age between 7-15 years.
  • GMFCS Level II or III.
  • Male and female participants.
  • Able to follow verbal instructions. Exclusion Criteria
  • Other neurological disorders.
  • Visual or hearing impairment.
  • Other types of cerebral palsy.
  • Severe cardiac disease.
  • Orthopedic surgery within previous six months.
  • Recent Botulinum toxin injection.
  • Children taking antispastic or antiepileptic medication.
  • Uncooperative participants.

Treatment and study plan

experimental group

Other

Virtual Reality Mediated Gamified Rehabilitation Program using Xbox Kinect combined with conventional physiotherapy.

Other names: Virtual Reality Mediated Gamified Rehabilitation Program

Control

Other

Conventional Physiotherapy Program

Other names: Conventional Physiotherapy

Primary outcomes

  1. Timed Up and Go Test

    Time frame: At baseline and after 6 weeks

    Timed Up and Go Test score measures the time in seconds it takes a person to stand up from a chair, walk 3 meters (10 feet), turn around, walk back, and sit down.

  2. Pediatric Balance Scale

    Time frame: baseline and after 6 weeks

    Pediatric Balance Scale examines functional balance in the context of everyday tasks in the pediatric population. It consists of 14 tasks.

  3. Trunk Impairment Scale

    Time frame: Baseline and after 6 weeks

    Trunk Impairment Scale is a 17-item physical test. It measures trunk motor control, balance, and coordination in a sitting position.

Secondary outcomes

  1. Gross Motor Function Classification System

    Time frame: Baseline and after 6 weeks

    Gross Motor Function Classification System is a five-level tool used to describe the self-initiated movement and mobility of children and youth with cerebral palsy.

Study contacts

Contact information is provided by the study sponsor or research team.

Hafsah Arshad, Phd*

CONTACT

[email protected]

03315165234

Tazveena IIUI, MS (paeds)

CONTACT

[email protected]

03139367436

Sponsors and collaborators

Lead sponsor

Ibadat International University, Islamabad

Other

Registry information

Official study title

Effect of Virtual Reality Mediated Gamified Rehabilitation Program in Children With Spastic Diplegic Cerebral Palsy

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 5, 2026
Registry last updated
Aug 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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