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OpenTrials
Active, not recruiting

NCT Number: NCT07636746

Interaction Between Head/Neck Position and C-MAC Blade Geometry on Videolaryngoscopic Intubation in Morbidly Obese Patients: A Randomized Controlled Trial

This study aims to explore the effect of head/neck position (sniffing vs ramped) and C-MAC blade geometry (MAC vs D-blade) on intubation in morbidly obese patients.

The patients will be randomized into 4 groups:

1. S MAC: Sniffing + MAC blade. 2. R MAC: Ramped + MAC blade. 3. S D-blade: Sniffing + D-blade. 4. R D-blade: Ramped + D-blade.

Active, not recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Morbid Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Obesity, Morbid Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ain Shams University

Cairo, Egypt, 00202

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-70 years.
  • BMI ≥ 40 kg/m².
  • ASA physical status III - IV.
  • Elective surgery requiring intubation.
  • Informed consent obtained.

Exclusion criteria

  • Anticipated difficult airway unrelated to obesity.
  • Cervical spine pathology.
  • Pregnancy.
  • Emergency surgery.
  • High aspiration risk.
  • OSA requiring CPAP >15 cmH₂O.
  • Need for awake intubation.

Treatment and study plan

Sniffing position and using MAC blade.

Device

Machintosch blade will be used in intubating patient in sniffing position

Ramped position and MAC Blade

Device

MAC blade will be used in intubating patient in ramped postion

videolaryngoscopy

Device

D-blade will be used in intubating patient in sniffing position

videolaryngosopy

Device

D-blade will be used in intubating patient in Ramped position

Primary outcomes

  1. Intubation time (seconds), from blade insertion to confirmed placement via capnography.

    Time frame: seconds

    Intubation time (seconds), from blade insertion to confirmed placement via capnography.

Interested in participating?

Active, not recruiting

This study is active but is not currently recruiting participants.

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Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Acronym: C-MAC

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 9, 2026
Registry last updated
Jun 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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