Cairo University Hospitals
Cairo, Egypt
Location status: Recruiting
NCT Number: NCT07443345
Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. It is defined by hypertension and involvement of multiple organ systems, including renal, hepatic, hematologic, and neurologic pathways. The interplay of endothelial dysfunction, capillary leakage, and disrupted fluid balance in these patients increases their susceptibility to perioperative pulmonary complications. Although respiratory complications in preeclampsia are clinically significant, the true incidence of postoperative diaphragmatic dysfunction in women with severe disease is not well established. Existing literature largely emphasizes general respiratory failure, pulmonary edema, or the need for mechanical ventilation, rather than specifically evaluating diaphragmatic performance with objective methods such as ultrasound. The current study sought to determine the incidence and identify risk factors for postoperative diaphragmatic dysfunction in women with severe preeclampsia following cesarean delivery.
Interested in participating?
Request Info20 year–40 year
Female
Observational
Cairo, Egypt
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: Diaphragmatic excursion is measured before and 24 hours after surgery.
diaphragmatic dysfunction is defined as a mean diaphragmatic excursion of less than 10 mm
Time frame: 24 hours after surgery
Percentage of change in diaphragmatic excursion from baseline to 24 hours after surgery
Time frame: 24 hours after surgery
Regression analysis to detect risk factors
Interested in participating?
Request InfoCairo University
Other
Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia With Severe Features Undergoing Cesarean Delivery: A Prospective Observational Study
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