Bezmialem Vakif University
Istanbul, Turkey (Türkiye)
NCT Number: NCT07441863
This ambispective observational cohort study aims to evaluate age-related differences in clinical outcomes among patients undergoing lung cancer surgery who received a structured comprehensive in-patient physiotherapy (CIPT) program as part of standard postoperative care. The CIPT program includes patient education, chest physiotherapy, breathing exercises, airway clearance techniques, early mobilization, postural exercises, and upper- and lower-extremity range-of-motion exercises during the postoperative hospital stay.
The primary outcome is hospital length of stay. Secondary outcomes include clinical parameters (blood pressure, resting heart rate, oxygen saturation, and respiratory rate), symptom-related outcomes (dyspnea, fatigue, and incisional pain), and inflammatory biomarkers (C-reactive protein, neutrophil-to-lymphocyte ratio, and albumin). Outcomes are analyzed according to predefined age groups (45-64 years and 65-90 years) to evaluate potential age-related differences.
Looking for future studies?
Notify Me45 year–90 year
All sexes
Observational
Istanbul, Turkey (Türkiye)
This ambispective observational cohort study evaluates age-related differences in clinical outcomes among patients undergoing lung cancer surgery who received a structured comprehensive in-patient physiotherapy (CIPT) program as part of standard postoperative care. Patients aged 45-90 years were included and classified into two predefined age groups: middle-aged (45-64 years) and older (65-90 years).
The CIPT program was initiated on the first day after transfer from the intensive care unit to the thoracic surgery ward and continued until hospital discharge. The program included patient education, breathing exercises, incentive spirometry, airway clearance techniques, early mobilization, postural exercises, and upper- and lower-extremity range-of-motion exercises. One session per day was supervised by a physiotherapist, with additional sessions performed independently by the patient or with caregiver assistance during hospitalization.
The primary outcome was hospital length of stay. Secondary outcomes included clinical parameters (blood pressure, resting heart rate, oxygen saturation, and respiratory rate), symptom-related outcomes (dyspnea, fatigue, and incisional pain), and inflammatory biomarkers (C-reactive protein [CRP], neutrophil-to-lymphocyte ratio [NLR], and albumin).
Outcomes were assessed during the postoperative inpatient period and compared between the predefined age groups. No randomization or non-intervention control group was included, as all participants received the same structured CIPT program as part of standard postoperative care.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The comprehensive in-patient physiotherapy (CIPT) program was provided as part of standard postoperative care following lung cancer surgery. The program included patient education, breathing exercises, incentive spirometry, airway clearance techniques, early mobilization, postural exercises, and upper- and lower-extremity range-of-motion exercises. It was initiated on the first day after transfer to the thoracic surgery ward and continued until hospital discharge. One session per day was supervised by a physiotherapist, with two additional sessions performed independently by the patient or with caregiver assistance
Time frame: Postoperative period, from ward admission after surgery until hospital discharge (maximum 30 postoperative days)
Length of hospital stay is defined as the number of days from postoperative admission to the ward until hospital discharge following lung cancer surgery.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Serum CRP levels (mg/L) will be measured to evaluate postoperative systemic inflammatory response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Peripheral oxygen saturation (%) will be measured using pulse oximetry to assess postoperative oxygenation status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
NLR will be calculated from complete blood count parameters to assess systemic inflammatory status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Serum albumin levels (g/dL) will be measured to assess nutritional status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Systolic blood pressure (mmHg) will be recorded to assess postoperative hemodynamic response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Diastolic blood pressure (mmHg) will be recorded to assess postoperative hemodynamic response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Heart rate (beats per minute) will be measured to evaluate cardiovascular response during the postoperative period.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Dyspnea severity will be assessed using the Modified Borg Dyspnea Scale (0-10), where 0 indicates "no breathlessness" and 10 indicates "maximal breathlessness."
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Fatigue will be assessed using the Borg Rating of Perceived Exertion (0-10), where higher scores indicate greater perceived fatigue.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Incisional pain will be evaluated using the Numeric Rating Scale (NRS, 0-10), where 0 represents "no pain" and 10 represents "worst imaginable pain."
Bezmialem Vakif University
Other
Age-Related Effects of a Structured Postoperative Pulmonary Physiotherapy Program After Lung Cancer Surgery: An Ambispective Observational Cohort Study in Middle-aged and Older Patients
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT00340405
Lung Cancer, Lung Diseases
Beijing, China
View Trial DetailsNCT05176860
Breast Cancer, Breast Diseases
Halifax, Nova Scotia, Canada
View Trial DetailsNCT06863233
Bronchial Neoplasms, Carcinoma, Bronchogenic
Basking Ridge, New Jersey, United States
View Trial DetailsNCT01562028
Bronchial Neoplasms, Carcinoma, Bronchogenic
Caen, France
View Trial Details