Mastication, Cognition, and Nutritional Status in Multiple Sclerosis

The aim of this study is to investigate the relationship between chewing function and cognitive functions, disease severity, and nutritional status in individuals diagnosed with Multiple Sclerosis

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Being 18 years of age or older

Exclusion criteria

Having a neurological or systemic disease other than Multiple Sclerosis that may affect chewing function
Inability to provide adequate communication or cooperation due to psychiatric disorders
Not being diagnosed with Multiple Sclerosis
Not volunteering to participate in the study
Presence of severe problems preventing questionnaire administration (visual and/or hearing impairments)
History or presence of psychiatric and/or other neurological disorders
Presence of severe neurological findings that may negatively affect cognitive performance (e.g., severe optic neuritis)
Use of medications affecting cognitive functions
Alcohol or substance use
Having experienced a relapse within the last month
Having received corticosteroid treatment within the last month
History of stroke, head and neck cancer, or rheumatic diseases that may affect swallowing and chewing performance

Treatment and study plan

Primary outcomes

Expanded Disability Status Scale (EDSS)

Time frame: Baseline
Montreal Cognitive Assessment (MoCA)

Time frame: Baseline
Turkish version of the Eating Assessment Scale (T-EAT-10)

Time frame: Baseline
Dysphagia in Multiple Sclerosis (DYMUS)

Time frame: Baseline
Test of Masticating and Swallowing Solids (TOMASS)

Time frame: Baseline
Mini Nutritional Assessment Short Form (MNA)

Time frame: Baseline

Study contacts

Contact information is provided by the study sponsor or research team.

Seda Nur Kemer, PhD

CONTACT

[email protected]

+905467861866

Sponsors and collaborators

Lead sponsor

Ondokuz Mayıs University

Other

Registry information

Official study title

Investigation of the Relationship Between Chewing Function and Cognitive Functions, Disease Severity, and Nutritional Status in Individuals With Multiple Sclerosis

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Feb 17, 2026
Registry last updated: Feb 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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