Ain Shams University Hospitals
Cairo, 11591, Egypt
Location status: Recruiting
NCT Number: NCT07399093
This study aims to assess the accuracy, repeatability, and reproducibility of preoperative evaluation of Inferior Vena Cava (IVC) collapsibility index and caval aorta index for prediction of hypotension after induction of general anesthesia.
Interested in participating?
Request Info18 year–40 year
All sexes
Observational
Cairo, 11591, Egypt
Location status: Recruiting
Post- anesthesia hypotension is of common occurrence, and it hampers tissue perfusion. The magnitude of hypotension is determined by the preoperative volume status, which varies depending on American Society of Anesthesiologists (ASA) physical status, preoperative comorbidities, preoperative medications, and fasting.
General anesthesia causes significant alterations in hemodynamics, as both inhalational and intravenous anesthetics cause bradycardia, decrease in systemic vascular resistance and vasodilatation, and decrease in myocardial contractility, cardiac output and stroke volume, with the absence of surgical stimulus, making induction of anesthesia is the most crucial period at which hypotension occurs.
Due to different definitions of hypotension and diverse patient populations, the effect of volume preload on prevention of hypotension is still controversial. Many recommendations to identified sonographic determination of inferior vena cava (IVC) collapsibility index (IVCCI) as non-invasive, and easy technique for evaluating volume status. Recent guidelines from the American Society of Echocardiography support the general use of IVCCI in assessing volume status.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Inferior vena cava (IVC) collapsibility index (IVCCI) will be measured.
The IVCCI is calculated using the following formula:
IVCCI = (maximum IVC diameter - minimum IVC diameter) / maximum IVC diameter * 100
The Inferior vena cava (IVC): Ao index will be derived by taking the ratio of the maximum IVC diameter during expiration and the maximal abdominal aortic diameter during systole.
Time frame: 15 minutes post-induction of general anesthesia.
Sensitivity of ultrasound guided Aorto-Caval index (IVC-AO) to predict hypotension will be recorded.
Time frame: 15 minutes post-induction of general anesthesia.
Specificity of ultrasound guided Aorto-Caval index (IVC-AO) to predict hypotension will be recorded.
Time frame: 15 minutes post-induction of general anesthesia.
Sensitivity of inferior vena cava (IVC) collapsibility index to predict hypotension will be recorded.
Time frame: 15 minutes post-induction of general anesthesia.
Specificity of inferior vena cava (IVC) collapsibility index to predict hypotension will be recorded.
Interested in participating?
Request InfoAin Shams University
Other
Preoperative Evaluation of IVC Collapsibility Index and Caval Aorta Index for Prediction of Hypotension After Induction of General Anesthesia in Patients Undergoing Craniotomy Surgeries
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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