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Completed

NCT Number: NCT07395661

Comparison Of Analgesic Methods İn Video-Assisted Thoracoscopic Surgery

Comparison of the Analgesic Efficacy of Serratus Anterior Plane Block and Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Video-Assisted Thoracoscopic Surgery Introduction and Objective: The aim of this study is to compare the postoperative analgesic efficacy of the serratus anterior plane block and serratus posterior superior intercostal plane block performed under ultrasonography guidance in patients undergoing video-assisted thoracoscopic surgery.

Patients with ASA grades I-III, aged 18-65, will be included in the study. Standard general anesthesia will be administered to the patients. Postoperative analgesia evaluation will be conducted using VAS and NRS scores at specific time points after surgery Additional analgesic requirements and patient satisfaction will be recorded.

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Key information

Conditions

VATS Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Management Pathological Conditions, Signs and Symptoms Perceptual Disorders Plane Blocks Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Health Siences Gazi Yasargil Training and Research Hospital

Diyarbakır, Kayapınar, 21100, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient aged between 18 and 65 years ASA physical status I-III Scheduled for elective video-assisted thoracoscopic surgery (VATS) Provided written information consent

Exclusion criteria

  • History of allergy or toxicity to local anesthetic agents
  • Known or suspected coagulopathy
  • Infection at the site of block injection
  • Advanced organ failure
  • Diagnosed mental retardation
  • Pregnancy
  • Pediatric patients
  • History of thoracotomy
  • Requirement for postoperative intubation
  • Emergency surgery
  • Refusal to participate in the study

Treatment and study plan

Ultrasound guided serratus anterior plane block

Procedure

Ultrasound-guided serratus anterior plane block was performed at the 4th intercostal level in the mid-axillary line using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the latissumus dorsi and serratus anterior muscles (unilateral)

Other names: serratus anterior plane block

Ultrasound guided serratus posterior superior intercostal plane block

Procedure

Ultrasound-guided serratus posterior superior intercostal plane block was performed using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the serratus posterior superior and intercostal muscles at the 3rd rib level via a posterior approach (unilateral)

Other names: Serratus posterior superior intercostal plane block

Primary outcomes

  1. Postoperative pain intensity

    Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours

    Postoperative pain intensity was assessed using the Visual Analog Scale (VAS) where 0 indicates no pain and 10 indicates the worst imaginable pain

Secondary outcomes

  1. Postoperative pain intensity assessed by Numeric Rating Scale (NRS)

    Time frame: 30 minutes, 1, 4, 8, 12, 24 hours after surgery

    Postoperative pain intensity will be assessed using the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst pain imaginable)

  2. Total 24-hour tramadol consumption

    Time frame: 24 hours after surgery

    Total amount of rescue tramadol administered within the first 24 postoperative hours, recorded in milligrams

  3. Rescue analgesia requirement

    Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours

    Proportion of patients requiring rescue analgesia (intravenous tramadol) at each postoperative assessment time point

  4. Adverse events

    Time frame: Within 24 hours after surgery

    Incidence of local anesthetic systemic toxicity, pneumothorax, hypotension, nausea/vomiting, and block-related complications

  5. Dynamic (movement-associated) postoperative pain intensity

    Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours

    Postoperative pain intensity during movement/coughing was assessed using the Visual Analog Scale (VAS), distinct from the primary outcome which assessed pain at rest (static VAS)

Sponsors and collaborators

Lead sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Other

Registry information

Official study title

Comparıson Of The Postoperatıve Analgesıc Effıcacy Of Serratus Anterıor Plane Block And Serratus Posterıor Superıor Intercostal Plane Block Performed Under Ultrasonography Guıdance In Vıdeo-Assısted Thoracoscopıc Surgery

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 9, 2026
Registry last updated
Aug 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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