Echocardiographic Assessment of Pulmonary Hypertension in Obstructive Sleep Apnea

This prospective, observational, cross-sectional study will be conducted in the pulmonology and sleep medicine departments of Assiut University. Patients diagnosed with OSA through overnight polysomnography will be assessed for the presence and severity of PH using echocardiography. The study aims to determine whether OSA serves as an independent risk factor for PH and whether the severity of OSA, as measured by apnea-hypopnea index (AHI) and oxygen desaturation index (ODI), correlates with echocardiographic indicators of PH. Data will be analyzed using standardized statistical methods to establish links between OSA severity and hemodynamic changes.

Inclusion criteria

Adults aged 18-65 years

Diagnosed with obstructive sleep apnea (OSA) by full-night polysomnography

Apnea-Hypopnea Index (AHI) ≥ 5 events/hour

Exclusion criteria

Secondary pulmonary hypertension due to:Chronic pulmonary diseases, Left ventricular heart disease and Chronic thromboembolic disorders

Use of pulmonary vasodilator therapy

Long-term oxygen therapy (LTOT)

Respiratory neuromuscular weakness

Chest wall deformities

End-organ failure (cardiac, renal, hepatic)

Malignancy

Obesity hypoventilation syndrome