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NCT Number: NCT07100561

30 Days and 90 Days Heart Failure Re-Admission at Komfo Anokye Teaching Hospital

In Ghana, about 88.3 per cent of cardiac admissions are due to Heart failure, making it the leading cause of admission due to heart conditions. Despite improved knowledge on heart failure and an increasing array of evidence-based guideline treatment options, there is still a significant readmission rate worldwide. This may be due to the underutilization of these evidence-based therapies or a lack of proper follow-up on these patients. Recurrent hospital admission is an independent predictor of death in heart failure. Strategies aimed at providing increased support at discharge and effective follow-up may be associated with lower readmission risk. This study aims to assess the effect of extensive post-discharge counselling and effective phone-based follow-up on the 30-day and 90-day heart failure readmission rate at a tertiary hospital in Ghana. This is a single-centre, pilot randomised controlled trial of heart failure patients admitted to the Komfo Anokye Teaching Hospital

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Komfo Anokye Teaching Hospital

Kumasi, Ashanti Region, Ghana

Location status: Recruiting

Location contact

Solomon Gyabaah

CONTACT

[email protected]

+233265763129

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • · Adults Aged 18 years and above
  • Diagnosed with heart failure
  • NYHA Class II-IV
  • Informed consent

Exclusion criteria

  • · NHYA class I
  • Patients who do not have access to a mobile phone

Treatment and study plan

Extensive post discharge counselling and phone-based follow up

Other

Counselling by their attending physicians plus Extensive post-discharge counselling from a study doctor/pharmacist/a trained nurse and telephone follow-ups in addition to their normal outpatient reviews. The telephone follow-ups will be weekly for the first 30 days and then 4 weekly till day 90.

Primary outcomes

  1. the occurrence of heart failure-related hospital readmission within 30 days and within 90 days after discharge from the index hospitalization

    Time frame: 90 days

    the occurrence of heart failure-related hospital readmission within 30 days and within 90 days after discharge from the index hospitalization

Secondary outcomes

  1. 1. Readmission rate of heart failure patients on guideline-directed heart failure medications

    Time frame: 90days

    The readmission rate of heart failure patients on guideline-directed medical therapy (GDMT) will be compared to those who are not on GDMT.

  2. Quality of life of the heart failure patients at 90 days

    Time frame: 90days

    Quality of life at 90 days will be measured using the Kansas City Cardiomyopathy Questionnaire (KCCQ).

  3. All-cause mortality within 30 and 90 days

    Time frame: 90 days

    . Assessing all-cause mortality will involve tracking total deaths from any reason within a population over the 90-day follow-up

  4. Caregiver burden in heart failure management

    Time frame: 30 days

    Caregiver burden will be assessed using the standard tool "Caregiver Burden Questionnaire - Heart Failure Version 3.0 (CBQ-HF)

Study contacts

Contact information is provided by the study sponsor or research team.

SOLOMON GYABAAH

CONTACT

[email protected]

+233265763129

Sponsors and collaborators

Lead sponsor

Komfo Anokye Teaching Hospital

Other

Registry information

Official study title

Extensive Post-discharge Counselling and Phone-based Follow-up Intervention to Reduce Heart Failure Readmission- A Pilot Randomized Control Trial

Acronym: HeFRA

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Aug 3, 2025
Registry last updated
Sep 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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