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OpenTrials
Active, not recruiting

NCT Number: NCT07093567

Opiophobia in Adults With Advanced Cancer

To explore the barriers and fears related to use of opioids among a population of adult outpatients with advanced cancer who continue to experience pain after receiving a prescription for opioid analgesia and hypothesized associations among opiophobia, anxiety, depression, pain intensity, pain interference, and opioid medication adherence.

Active, not recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Cancer Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

The University of Texas M. D. Anderson Cancer Center

Houston, Texas, 77030, United States

About this study

Primary Objective:

To explore the barriers and fears related to use of opioids among a population of adult outpatients with advanced cancer who continue to experience pain after receiving a prescription for opioid analgesia.

Secondary Objective:

To examine associations among opiophobia, anxiety, depression, pain intensity, pain interference, and opioid medication adherence among adults with advanced cancer who report undermanaged pain during the first week after receiving a prescription for an opioid analgesic.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients with advanced cancer (defined as cancer that is unlikely to be cured and is locally advanced or distantly metastasized
  • Pain is the documented reason for the Supportive Care consultation
  • Have a prescription for an opioid analgesic
  • Able to read, speak, and consent in English.

Exclusion criteria

  • Age less than 18 years
  • Do not have a prescription for an opioid analgesic
  • Individuals for whom there is documentation of inability to provide consent in the medical record
  • Women who are pregnant
  • Patients with a substance use disorder (including alcohol use disorder and excluding tobacco use disorder) documented in the electronic health record under History of Present Illness or in the Medical History.

Treatment and study plan

Primary outcomes

  1. Barriers Questionnaire (BQ-13)

    Time frame: Through study completion; an average of 1 year

Interested in participating?

Active, not recruiting

This study is active but is not currently recruiting participants.

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Sponsors and collaborators

Lead sponsor

M.D. Anderson Cancer Center

Other

Registry information

Important dates

Study start
2025
Primary completion
2029
Study completion
2031
First posted
Jul 30, 2025
Registry last updated
Sep 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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