A Prospective Study on Clinical Effectiveness After SMILE Versus SMILE Xtra in Myopia

Inclusion criteria

• Age between 18 and 50 years.
• High myopia with a manifest refraction spherical equivalent (MRSE) - 6.00D～-10.00D and refractive changes within ± 0.50D in the past two years;
• Best corrected distance visual acuity (CDVA) ≥ 20/25.
• Preoperative refractive status is stable (myopia progression not exceeding 0.50D per year for at least 2 years).
• Predicted residual stromal thickness (RST) ≥ 250μm after lenticule removal. 6.Soft contact lenses discontinued for at least 1 week, rigid contact lenses for at least 3 weeks, and orthokeratology lenses for at least 3 months.

Exclusion criteria

• The presence of other eye diseases: keratoconus or suspected keratoconus, active keratoconjunctivitis, severe dry eye, glaucoma, retinal diseases such as retinal tears or macular degeneration, etc.,
• The presence of significant corneal scarring or cataracts affects observation.
• Systemic diseases such as active systemic inflammation, connective tissue diseases, other conditions that prevent