Hemodynamic Monitoring Carotid Surgery

patients scheduled for carotid endoarterectomy will be randomly assigned to a group in which arterial hypotension will be avoided by a predictive haemodynamic approach or to a group in which arterial hypotension will be treated in a standard manner

Recruiting

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Key information

Conditions

Carotid Artery Diseases Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Haemodynamic Monitoring Nervous System Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Fondazione Policlinico Universitario Policlinico Gemelli

Rome, Italy

Location status: Recruiting

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

>18 years old patients

Exclusion criteria

Body MassIndex > 35 Kg /m2;
Atrial Fibrillation
Urgent surgery
Pregnancy

Treatment and study plan

predictive approach to hemodynamic management

Other

vasoactive drugs and fluids will be given based on the hypotension prediction index

Primary outcomes

stump pressure

Time frame: during surgery

we will compare the value of stump pressure between the two groups. the stump pressure will be measured after clamping the common and external carotid vessels

Interested in participating?

Recruiting

Interested in participating?

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Sponsors and collaborators

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Other

Registry information

Official study title

Effect of a Predictive Hemodynamic Approach on the Stump Pressure During Carotid Endoartectomy: a Randomized Controlled Trial

Acronym: PREST

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2027
First posted: Apr 13, 2025
Registry last updated: May 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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