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NCT Number: NCT06606717

Effects of Resistance-band Training and Creatine and Whey Protein

The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition (whole-body lean tissue mass, total body water), arm and leg muscle thickness, upper- and lower-body muscle performance (i.e., strength, endurance) and functional ability (walking speed, balance). A secondary purpose of this research is to examine the effects of supplementation cessation (i.e., no creatine and/or whey protein supplementation) during the final 10 weeks of the 20-week resistance-band training program on these measures.

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Key information

Conditions

Sarcopenia in Elderly

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Regina

Regina, Saskatchewan, S4S 0A2, Canada

Location status: Recruiting

About this study

Sarcopenia, characterized by the age-related reduction in strength, muscle mass, and physical function, decreases the ability to perform activities of daily living. Physical inactivity and inadequate nutrition are contributing factors to the development of sarcopenia. Resistance training is a safe, viable and effective intervention which increases measures of muscle and bone mass, muscle performance (i.e., strength, endurance) and functional ability in older adults. However, older adults indicate that high costs and difficulty finding training programming and/or facilities are barriers to participating in resistance training. Home-based resistance-band training is safe, effective and serves as a viable alternative to traditional resistance training (i.e., involving free-weights and machine-based equipment). From a healthy aging perspective, resistance-band training elicits similar improvements in strength (primary indicator of sarcopenia) and functional ability compared to traditional resistance training in older adults. In addition to resistance training (involving resistance-bands), creatine and whey protein supplementations have also been shown to have favorable effects on measures of muscle, bone and functional ability in older adults. However, no study has examined the effects of resistance-band training and creatine and whey protein supplementation in older adults.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Untrained (defined as those performing ≤ 1 resistance training session per week for ≥ 6 weeks prior to the start of the study)

Exclusion criteria

  • Taking creatine monohydrate within 30 days prior to the start of the study
  • Currently ingesting whey protein
  • Have pre-existing allergies to latex, fruit, dairy, nuts, seafood and mustard

Treatment and study plan

Creatine Whey Protein

Dietary Supplement

3 grams creatine + 30 grams whey protein

Whey Protein

Dietary Supplement

30 grams Whey Protein

Primary outcomes

  1. Whole-body lean mass (kg)

    Time frame: baseline, week 10, week 20

    Bioelectrical impedance analysis

  2. Strength (kg)

    Time frame: baseline, week 10, week 20

    1-repetition maximum leg press and chest press

  3. Endurance (number of repetitions to fatigue)

    Time frame: baseline, week 10, week 20

    Leg press and chest press

  4. Balance (Centre of Pressure)

    Time frame: baseline, week 10, week 20

    Force Plate

  5. Hydration (kg)

    Time frame: baseline, week 10, week 20

    Bioelectrical impedance analysis

  6. Gait Speed (meters)

    Time frame: baseline, week 10, week 20

    Walking distance

  7. Muscle Hypertrophy (cm)

    Time frame: baseline, week 10, week 20

    B-mode ultrasound

Interested in participating?

Recruiting

Interested in participating?

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Sponsors and collaborators

Lead sponsor

University of Regina

Other

Collaborators

  • Iovate Health Sciences International Inc

Registry information

Official study title

Effects of Resistance-band Training and Nutritional Supplementation in Healthy Older Adults

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Sep 23, 2024
Registry last updated
Sep 23, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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