Two Liberty Place
Philadelphia, Pennsylvania, 19102, United States
NCT Number: NCT06555484
Forty healthy adults (i.e., not recruited with respect to any particular diagnosis) are each alternately provided with supplemental oxygen and air via nasal cannula at about 6 Liters per Minute (LPM), while completing memory tests.
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Notify Me22 year–80 year
All sexes
Interventional
Not applicable
Philadelphia, Pennsylvania, 19102, United States
Prior studies have reported that supplemental oxygen can confer acute benefits to cognition. Here, the investigators seek to replicate/extend such findings by assessing whether such benefits can be seen using an Inogen oxygen concentrator with subjects with an average age around 65 years old. The investigators include a standard measure of cognition previously reported to be sensitive to supplemental oxygen (2-back test) and a novel, in-development adaptation of a memory test for medical-related content (Medical icons spatial test).
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Subjects are intended to represent "healthy adults." Patients will include a mix of self-reported gender and ethnic/racial identification.
Exclusion criteria
Subjects repeatedly complete memory tests, either first while breathing supplemental oxygen or first while breathing "supplemental air" (in an order randomly assigned).
Time frame: At baseline and 5 mins post-intervention exposure
# correct on 2-back test
Time frame: At baseline and 5 mins post-intervention exposure
New Medical Icons Spatial Test
Looking for future studies?
Notify MeInogen Inc.
Industry
Acute Effects of Supplemental Oxygen on Memory in Healthy Older Adults: a Double-Blind Within-Subject Crossover Study
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