B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers

Examine the role of B-catenin in differentiation of cutaneous squamous cell carcinoma from other lesions that may be similar to it

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Key information

Conditions

Cutaneous Squamous Cell Carcinoma

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag University hospital

Sohag, Egypt

Location status: Recruiting

About this study

Skin cancer is one of the most common form of cancer worldwide. Cutaneous squamous cell carcinoma is one of most common skin tumers that caused by many factors as ultra violet ,ionizing radiation and others . It was an advanced spectrum ranging from actinic keratosis to invasive and metastatic squmous cell carcinoma. Correct identification of cutaneous squamous cell carcinoma is a challenge as it has both clinically and histopathologically mimickers.

So the aim of this study is to identify the expression of B-catenin in cutaneous Squamous cell carcinoma and its mimickers.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

tissue blocks with sufficient materials Cases with sufficient data

Exclusion criteria

tissue blocks with insufficient and necrotic materials. Casas with insufficient data

Treatment and study plan

Immunohistochemical staining

Biological

Staining of cutanous squamous cell carcinoma and its mimickers by monoclonal antibodies against human B-catenin by immunohistochemical procedures

Primary outcomes

Detection of B-catenin expression in cutanous squamous cell carcinoma and its mimickers

Time frame: 6 month

Detection of expression of B-catenin in cutaneous squamous cell carcinoma and its mimickers by immunohistochemical procedures using antihuman B-catenin monoclonal antibodies

Interested in participating?

Recruiting

Interested in participating?

Request Info

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Expression of B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2025
First posted: Aug 5, 2024
Registry last updated: Aug 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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