[11C]Metomidate PET-CT vs Usual Care for People With Primary Aldosteronism: a Proof-of-concept Study
NCT07814105
Adrenal Gland Diseases, Adrenocortical Hyperfunction
Shatin, Hong Kong
View Trial DetailsNCT Number: NCT06534268
This study employs a prospective, single-center, open, observational research design to evaluate postoperative adrenal cortical function in patients with primary aldosteronism (PA) and to explore indicators predicting postoperative adrenal insufficiency and their predictive efficacy
Trial opening soon.
Get Notified18 year–75 year
All sexes
Observational
Patients suspected of having primary aldosteronism and admitted for treatment, who are diagnosed with primary aldosteronism through at least one confirmatory test, and subsequently diagnosed with unilateral primary aldosteronism via bilateral adrenal vein sampling and ACTH stimulation test, will undergo surgery. Those who have an ACTH stimulation test within one week postoperatively will be included in the study.
This study employs a prospective, single-center, open, observational research design to evaluate postoperative adrenal cortical function in patients with primary aldosteronism (PA) and to explore indicators predicting postoperative adrenal insufficiency and their predictive efficacy
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 1 day
age in years and sex (female or male) of patients
Time frame: 1 day
BMI(body mess index) in kg/m^2= (weight in kg) /(height in m)^2
Time frame: 1day
serum hormone level
Time frame: 1 day
glucose metabolism, lipid metabolism, liver and kidney function, electrolytes, etc
Time frame: 1day
cortisol and aldosterone levels
Time frame: 1day
cortisol and aldosterone levels
Time frame: 1day
blood lipid levels
Time frame: 1day
0-minute、30-minute、60-minute 、120-minute and 180-minute blood glucose levels after OGTT
Time frame: 1day
sodium, potassium, chloride, calcium, and phosphorus ion levels
Time frame: 1day
Creatinine, blood urea nitrogen (BUN), and uric acid levels
Time frame: 1day
cortisol and aldosterone serum hormone level
Time frame: 1day
blood lipid levels
Time frame: 1day
0-minute、30-minute、60-minute 、120-minute and 180-minute blood glucose levels after OGTT
Time frame: 1 day
Creatinine, blood urea nitrogen (BUN), and uric acid levels
Trial opening soon.
Get NotifiedRuijin Hospital
Other
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