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NCT Number: NCT06482996

General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery

The primary aim of the study is to investigate the correlation between preoperative hemodynamics and frailty scores in patients undergoing cataract surgery under general anesthesia. The secondary objective is to explore the relationship between preoperative and postoperative intraocular pressure changes and frailty scores.

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Key information

Conditions

Cataract Eye Diseases Frailty Lens Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

65 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Umraniye Education and Research hospital

Istanbul, 34764, Turkey (Türkiye)

Location status: Recruiting

About this study

Cataract stands as a significant cause of vision impairment worldwide, notably prevalent among the elderly. This study aims to explore the changes in intraocular pressure (IOP) and blood pressure under general anesthesia during cataract surgery in frail geriatric patients. The research emphasizes the critical role of frailty assessment in determining surgical risks among elderly surgical patients. It focuses on the hypothesis that frail individuals undergoing cataract surgery under general anesthesia might experience more pronounced effects on IOP and blood pressure during the surgical procedure compared to prefrail counterparts. This study emerges as a crucial step in understanding the impact of preoperative frailty assessment on surgical planning and outcomes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 65-85 age
  • ASA I-III
  • cataract surgery with genel anesthesia

Exclusion criteria

  • cerebrovascular disease,
  • mental retardation and psychiatric illness,
  • pulmonary infection, history of advanced COPD or respiratory failure,
  • EF less than 40%, presence of cardiovascular disease,
  • bleeding diathesis,
  • renal and hepatic insufficiency,
  • presence of diabetes mellitus, diuretic/mannitol users,
  • substance abuse
  • BMI >30

Treatment and study plan

Intraocular pressure (IOP) was measured

Other

The Frail Scale was used to assess the frailty of the patients.Intraocular pressure (IOP) was measured before anesthesia, 5 minutes after induction of anesthesia and 1 hour postoperatively. IOP was measured using a Tono-pen tonometer (AccuPen). The normal range of IOP is 11-21 mmHg (mean 16 mmHg) and values above 24 mmHg are pathologic.

Primary outcomes

  1. intraocular pressure during genel anesthesia

    Time frame: through study completion, an average of 1 day

    intraocular pressure (mmHg)

Secondary outcomes

  1. hemodynamic data

    Time frame: through study completion, an average of 1 day

    mean arterial pressure (mmHg)

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Sponsors and collaborators

Lead sponsor

Umraniye Education and Research Hospital

Other Gov

Registry information

Official study title

the Impact of General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Jul 1, 2024
Registry last updated
Nov 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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