USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
Location status: Recruiting
Recruiting
NCT Number: NCT06420219
An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence
This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
PRIMARY OBJECTIVE:
I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes.
OUTLINE: This is an observational study.
Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Diagnosis/disease status: New diagnosis of head and neck cancer
- Allowable type and amount of prior therapy: No prior treatment
- Age ≥ 18 years.
- Ability to understand and the willingness to sign a written informed consent.
Exclusion criteria
- Patients who have had treatment of head and neck cancer
Treatment and study plan
Non-Interventional Study
OtherNon-interventional study
Primary outcomes
-
Overall survival
Time frame: Up to 5 years
-
Disease free survival
Time frame: Up to 5 years
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
University of Southern California
Other
Collaborators
- American Academy of Otolaryngology-Head and Neck Surgery Foundation
- National Cancer Institute (NCI)
Registry information
Important dates
- Study start
- 2024
- Primary completion
- 2028
- Study completion
- 2029
- First posted
- May 17, 2024
- Registry last updated
- Apr 28, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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