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Completed

NCT Number: NCT06350253

Comparison Of Measured To Predicted Resting Metabolism

The purpose of this study is to compare RMR values from the BIA, predicted equations, and indirect calorimetry.

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Key information

Conditions

Body Weight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ohio University Exercise Physiology Lab

Athens, Ohio, 45701, United States

About this study

Resting metabolic rate (RMR) describes the number of calories a person utilizes while at rest. The gold standard measurement is via inspired and expired air using a metabolic cart. However, researchers have established estimation equations and the use of body composition analysis to predict RMR when a metabolic cart is unavailable. The accuracy of the predicted equations and whole-body bioelectrical impedance (BIA) machines that produce this data is unknown. Therefore, the purpose of this study is to compare RMR values from the BIA, predicted equations, and indirect calorimetry.

Aim 1: to compare measured RMR from indirect calorimetry to values provided by the InBody 770 BIA machine and to established gender and age-appropriate prediction equations.

Aim 2: to compare RMR measured from indirect calorimetry using a metabolic cart (Gold Standard) to the Medgem handheld indirect calorimeter (FDA approved device).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men & women, aged 18-60

Exclusion criteria

  • Have any known or suspected metabolic diseases such as diabetes, thyroid disorder, or high cholesterol
  • Have any known or suspected cardiovascular or pulmonary diseases such as hypertension
  • Are currently on beta blockers, taking antihypertensives, or antidepressants
  • Current smoker or quit less than a year ago
  • Unwilling to provide finger stick and urine sample

Treatment and study plan

Metabolic cart

Diagnostic Test

RMR measurement via metabolic cart

MedGem

Diagnostic Test

RMR measurement via MedGem

BIA

Diagnostic Test

RMR estimation from BIA analysis

Primary outcomes

  1. Resting metabolic rate

    Time frame: day 1

Interested in participating?

Completed

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Sponsors and collaborators

Lead sponsor

Ohio University

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Apr 5, 2024
Registry last updated
Jul 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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