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Completed

NCT Number: NCT06331221

Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense

The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.

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Key information

Conditions

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Faculdade de Desporto, Universidade do Porto

Porto, 4200, Portugal

About this study

A randomized controlled crossover trial will be conducted at a biomechanics laboratory with healthy males. All participants will perform with a washout period of 1 week: a control condition (5-minute rest) and 4 local muscle fatigue protocols (concentric of quadriceps; concentric of hamstrings; eccentric of quadriceps; eccentric of hamstrings) in an isokinetic dynamometer at 30º/s. Three maximum voluntary isometric contractions (MVIC) of quadriceps and hamstrings will also be assessed in the beginning of all conditions.

Knee joint position sense will be assessed before and immediately after the fatigue protocols/control condition, through active concentric and eccentric positionings/repositionings, in sitting and prone positions, to a target range of 45º of knee flexion in an isokinetic dynamometer. Surface electromyography electrodes will also be placed on the vastus lateralis and biceps femoris during all procedures.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • males aged between 18 and 30 years;
  • without current or previous knee pathology or surgery;
  • with a low or moderate physical activity level, according to the International Physical Activity Questionnaire;
  • normal Body Mass Index (under 24.9 kg/m2), according to the World Health Organization.

Exclusion criteria

  • those with cardiorespiratory, neurological or vestibular pathologies;
  • with positive knee integrity tests (anterior drawer, Lachman's test, posterior drawer; valgus and varus stress testes); and
  • those taking any medication that can affect motor control (sedatives, anxiolytics, antibiotics, analgesics, NSAIDs or myorelaxants).

Treatment and study plan

Muscle fatigue protocol

Other

Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.

Primary outcomes

  1. Absolute angular error

    Time frame: Change from Baseline (Before) to Immediately after interventions or control (After)

    The absolute value of the difference between the target range and the achieved range

  2. Relative angular error

    Time frame: Change from Baseline (Before) to Immediately after interventions or control (After)

    The arithmetic difference between the target range and the range achieved

  3. Variable angular error

    Time frame: Change from Baseline (Before) to Immediately after interventions or control (After)

    The standard deviation of the 3 repositionings

Sponsors and collaborators

Lead sponsor

Universidade do Porto

Other

Registry information

Official study title

Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense: a Randomized Controlled Crossover Trial

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Mar 26, 2024
Registry last updated
Jul 11, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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