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NCT Number: NCT06323629

Effects of Recursive Self-feedback on Speech Production in Aphasia

The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia). The main question it aims to answer is:

• To what extent can stroke survivors with aphasia use their self-feedback alone to improve their spontaneous speech production?

Participants will be engaged in the following activities:

* They will perform language and cognitive tasks. * Afterwards, they will receive treatments using tablets and headphones at no cost to them. * The experimental treatments (recursive self-feedback procedures) entails responding to prompts, listening to playbacks of their speech response and attempt to minimize/correct the errors in the next attempt. This process will be repeated multiple times per prompt. * The experimental treatments are two: an adaptive version that adapts the complexity of the treatment prompt and a non-adaptive version that does not adapt task complexity. * Researchers will compare the experimental treatments to see if both have similar effects on improving spontaneous speech production.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Brain and Aphasia Recovery Lab, PCD 1030, Department of Communication Sciences and Disorders, University of South Florida

Tampa, Florida, 33620, United States

Location status: Recruiting

Location contact

Gerald C Imaezue, PhD

CONTACT

[email protected]

8139742464

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 6 months post left hemisphere stroke
  • Aphasia due to left hemisphere stroke
  • Dominant English speaker

Exclusion criteria

  • Speech-language deficits due to neurological insults such as Parkinson's disease, neurodegenerative conditions etc.
  • Uncorrected sensory impairments.
  • Language comprehension impairment.
  • Severe cognitive impairment.

Treatment and study plan

Adaptive recursive self-feedback procedure

Behavioral

The intervention uses self-feedback alone to improve speech production. It adapts the complexity of the treatment tasks.

Non-adaptive recursive self-feedback procedure

Behavioral

The intervention uses self-feedback alone to improve speech production. However, it does not adapt the complexity of the treatment tasks.

Primary outcomes

  1. Speaking rate

    Time frame: Within 1 week before treatment and within 1 week after treatment.

    Correct words produced per minute

  2. Speech initiation latency in milliseconds

    Time frame: Within 1 week before treatment and within 1 week after treatment.

    Latency before retrieving the first correct word in an utterance.

Study contacts

Contact information is provided by the study sponsor or research team.

Gerald C. Imaezue, PhD

CONTACT

[email protected]

(813)974-2464

William Burgin, MD

CONTACT

[email protected]

813-259-8577

Sponsors and collaborators

Lead sponsor

University of South Florida

Other

Collaborators

  • Center for Smart Use of Technologies to Assess Real-world Outcomes

Registry information

Official study title

Recursive Self-feedback Procedures for Improving Spontaneous Speech Production in Patients With Chronic Aphasia

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Mar 21, 2024
Registry last updated
Sep 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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