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NCT Number: NCT06323070

Effects of Watermelon or Low-fat Cookie Consumption on Wellness

The objective of the proposed research is to determine the effects of fresh watermelon consumption on physiological indicators of wellness regarding sexual, skin and gut health in adults.

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Key information

Conditions

Overweight and Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

School of Exercise and Nutritional Sciences

San Diego, California, 92182, United States

Location status: Recruiting

Location contact

Mee Young Hong, PhD

CONTACT

[email protected]

619-594-2392

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Generally healthy subjects
  • BMI 20-40 kg/m2

Exclusion criteria

  • Smoker
  • Pregnant woman
  • Required antibiotics use
  • Required dietary supplement use
  • Required medication of metabolic disorders, mental health and sexual health
  • Allergy to watermelon or wheat

Treatment and study plan

Low-fat cookies

Other

To determine the effects of low-fat cookie consumption on physiological indicators of wellness regarding sexual, skin, and gut health

Watermelon

Other

To determine the effects of watermelon consumption on physiological indicators of wellness regarding sexual, skin, and gut health

Primary outcomes

  1. Change of sexual health questionnaire scores

    Time frame: Baseline and week 4

    Change of sexual health questionnaire scores will be determined to examine effects of watermelon consumption vs low-fat cookies.

  2. Change of skin hydration scores

    Time frame: Baseline, 1 min post application and week 4 consumption

    Change of skin hydration scores will be determined to examine effects of watermelon consumption vs low-fat cookies.

  3. Change of microbiome diversity

    Time frame: Baseline and week 4

    Change of microbiome diversity will be determined to examine effects of watermelon consumption vs low-fat cookies.

Secondary outcomes

  1. Change of depression questionnaire scores

    Time frame: Baseline and week 4

    Change of depression questionnaire scores will be determined to examine effects of watermelon consumption vs low-fat cookies.

  2. Changes of trimethylamine N-oxide (TMAO) levels

    Time frame: Baseline and week 4

    Changes in trimethylamine N-oxide (TMAO) levels will be determined to examine the effects of watermelon consumption vs low-fat cookies.

  3. Changes of cholesterol levels

    Time frame: Baseline and week 4

    Changes in cholesterol levels will be determined to examine the effects of watermelon consumption vs low-fat cookies.

Study contacts

Contact information is provided by the study sponsor or research team.

Mee Young Hong, PhD

CONTACT

[email protected]

619-594-2392

Sponsors and collaborators

Lead sponsor

San Diego State University

Other

Registry information

Important dates

Study start
2024
Primary completion
2028
Study completion
2028
First posted
Mar 21, 2024
Registry last updated
Aug 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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