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NCT Number: NCT06126055

Endoscopic Band Ligation for Treating Reflux Disease

GERD is a chronic disease the require different treatment modalities; non have proven long term efficacy with concerns about their safety. The use of band ligation in endoscopy appears safe, repeatable with short learning curve. Placing multiple bands at the Z-line can create a fibrous ring in the distal esophagus acting as a barrier against reflux of gastric content.

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Key information

Conditions

GERD Deglutition Disorders Digestive System Diseases Esophageal Diseases Esophageal Motility Disorders Gastroesophageal Reflux Gastrointestinal Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Endoscopy Unit Cairo University

Cairo, Egypt

About this study

The aim of the study is the complete resolution of reflux symptoms without the use of any drug.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Symptomatic GERD

Exclusion criteria

  • Any previous surgery for GERD

Treatment and study plan

Band Ligation

Device

Placing bands in distal esophagus

Primary outcomes

  1. Endoscopic Band Ligation for GERD

    Time frame: 1 month

    Resolution of reflux symptoms and stopping proton pump inhibitors.

Interested in participating?

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Trial opening soon.

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Sponsors and collaborators

Lead sponsor

El Katib Hospital

Other

Collaborators

  • Kasr El Aini Hospital

Registry information

Official study title

EndoBand: Endoscopic Band Ligation for Treating Reflux Disease (GERD)

Important dates

Study start
2027
Primary completion
2028
Study completion
2029
First posted
Nov 13, 2023
Registry last updated
Sep 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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