Clinical Evaluation and Assesment of Ginigivitis Patients Treated by Yarrow Natural Extract in Compare to a Contro Group

A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry and Periodontology, Dental School and Hospital, Minia university to compare the antibacterial activity of yarrow Moringa herbal combinations nanoparticles in compared to Chlorhexidine as a potential treatment for gingivitis.

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Key information

Conditions

Gingivitis Gingival Diseases Infections Mouth Diseases Periodontal Diseases Stomatognathic Diseases

Age range

25 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Soad A. Mohamad

Minya, Minya Governorate, 05673, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

a minimum of four natural uncrowned teeth in one quadrant present
good general health
can follow instructions

Exclusion criteria

were pregnant or breastfeeding
evidence of antibiotic use during the 4 weeks prior to the study
were allergic to personal care/consumer products or their ingredients

Treatment and study plan

Yarrow and moringa mixture

Drug

yarrow and moringa mixture nano particles loaded on buccal film

Primary outcomes

antibacterial and anti inflammatory activities

Time frame: two weeks

scoring of erthymia and pain (no pain=0) and the other end (worst pain=10).

Sponsors and collaborators

Lead sponsor

Deraya University

Other

Registry information

Official study title

Clinical Assessment of Antibacterial Anti-inflammatory Activities of Yarrow Moringa Herbal Combinations in Bucco Adhesive Films

Important dates

Study start: 2022
Primary completion: 2022
Study completion: 2023
First posted: Oct 6, 2023
Registry last updated: Oct 6, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed