Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

PRIMARY OBJECTIVE:

I. To evaluate the impact of social-environmental risk factors on changes in Charlson Comorbidity Index over time for adolescent and young adult cancer survivors.

OUTLINE: This is an observational study.

Patients complete questionnaires and undergo collection of blood samples on study.

Inclusion criteria

• Patient must be >= 18 years of age at the time of registration
• Patient must have been between the ages of 15-39 at the time of their first primary cancer diagnosis of Hodgkin lymphoma or non-Hodgkin lymphoma (NHL) or leukemia (acute lymphoblastic leukemia [ALL] only)
• Patient must have completed therapy (with a complete response, per clinician determination) at the time of registration
• Patients last date of prior systemic therapy for first primary diagnosis for Hodgkin lymphoma or non-Hodgkin lymphoma or leukemia (ALL) must have been within 3 years prior to registration

• NOTE: Systemic therapy refers to all anti-cancer therapy, including but not limited to chemotherapy, intravenous (IV) or oral targeted medications, or radiation, and administered via a clinical trial or standard approach
• Patient must have an Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-3
• Patient must be English speaking in order to be able to complete the required QOL forms on this study

• NOTE: Sites cannot translate the associated QOL forms
• Patient must not be receiving active therapy for Hodgkin lymphoma or non-Hodgkin lymphoma or leukemia
• Patient must have internet access through computer, tablet, or smartphone
• Patient must have email address
• Patient must have the ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) or caregiver and/or family member available will also be considered eligible