Retrospective Evaluation of Delirium Data From Previous Study Patients for Studies at the Clinic for Anesthesiology and Intensive Care Medicine CCM/CVK/CBF

Validated delirium scoring (points, duration and severity)

Sedation is measured by the Richmond Agitation Sedation Scale

Soci-economic information is collected by FIMA

Soci-economic information is collected by the Nikolaus-score (social situation), 1. Subscale

Soci-economic information is collected by items on socioeconomic status from the Federal Health Survey of 1998

Comorbidities are new diagnoses from hospital records.

Comorbidity scores

Consumption of alcohol is measured by AUDIT (Alcohol Use Disorders Identification Tests)

Consumption of and nicotine is measured by Fagerström Test for Cigarette Dependence (FTCD). Questionnaire scored 0-10 points with Total Score equal to the sum of all points

Consumption of nicotine is measured by Smocking Pack Years (SPY)

Previous consumption of nicotine is measured by History of Smoking.

Level of education is measured by ISCED (International Standard Classification of Education)

Quality of life is measured by CarerQoL

Quality of life is measured by EQ-5D.An index calculated from the five EQ-5D (3L and 5L) dimensions by attaching specific weights to each severity level in each dimension.

Quality of life is measured by WHO-5. WHO-5 is a short and generic global rating scale measuring subjective well-being, the respondent is asked to rate how well each of the 5 statements applies to him or her when considering the last 14 days. Each of the 5 items is scored from 5 (all of the time) to 0 (none of the time). The raw score ranges from 0 (absence of well-being) to 25 (maximal well-being). Scores are then converted to a percentage scale from 0 (absent) to 100 (maximal). Higher scores represent greater psychological well-being.

Quality of life is measured by SF-12 (Short form health survey)

Instrumental Activities of Daily Living (IADLs) < 8

Activities of Daily Living (ADLs) < 100

Depression 1 is measured by PHQ-8 (Patient Health Questionnaire depression scale)

Depression 2 is measured by GDS (Geriatric Depression Scale)

Depression 3 is measured by HADS (Hospital Anxiety and Depression Scale)

Depression 4 is measured by CDS (Cornel Depression Scale)

Anxiety is measured by GAD-7 (Generalized Anxiety Disorder 7)

Anxiety 2 is measured by FAS (Faces Anxiety Scale)

Anxiety 2 is measured by GAD-7

Pain is measured by numeric pain scales (minimum = 0, maximum = 10).

The medication administered during the hospital stay is documented.

Measured by anticholinergic drug scale

Frailty is measured with a modified frailty score according to Fried´s frailty phenotype assessment.

Nutritional status 1 is measured by calf circumference

Nutritional status 2 is measured by arm circumference

Nutritional status 3 is measured by changes in weight

Nutritional status 4 is measured by changes in body mass index

Nutritional status 5 is measured by previous weight history (3 months)

Nutritional status 6 is measured by Medi-Score

Nutritional status 7 is measured by MNA-SF

Nutritional status 8 is measured by Sarcopenia

Nutritional status 9 is measured by Nutritional Risk Screening (NRS 2002)

Nutritional status 10 is measured by AKE Screening

Mobility 1 is measured with the Timed up and Go

Mobility 2 is measured with a walking test: Slowness: Calculated after walking 3 meters, adjusted for sex and height, according to Fried. The cut-off points for 3 meters were established as, in men: height ≤173 cm and time ≥4.59 s (equivalent to 0.65 m/s); height >1.73 cm and time ≥3.93 s (equivalent to 0.76 m/s); and for women: height ≤1.59 cm and time ≥4.59 s (0.65 m/s); and height >1.59 cm and time ≥3.93 s (0.76 m/s).

Laboratory results in the hospital including hemoglobin, lymphocytes, total neutrophils, platelet count, white blood cell (WBC) count and inflammatory markers from blood samples.

Laboratory results in the hospital from serum samples

Laboratory results in the hospital from urine samples

Laboratory results in the hospital from liquor samples

The sedation was measured intraoperatively processed electroencephalogram (EEG) Full-brain EEG recording with surface electrodes, raw EEG analysis measured during the operation.

Type of operation is measured by OPS-Code

Type of operation is measured in minutes

There are four main categories of anesthesia used during surgery and other procedures: general anesthesia, regional anesthesia, sedation (sometimes called "monitored anesthesia care"), and local anesthesia.

Duration of anesthesia is measured in minutes.

Hospital stay is measured in days.

Intensive care unit stay is measured in hours.

Organ complications are recorded in hospital records

Discharge criteria are measured at hospital discharge by Post Anesthetic Discharge Scoring System (PADS) Score

Mortality rate is measured after 1,2,3,4 and 5 years

Identification of study data with a high impact on delirium from the study databases

Questions measuring personal satisfaction with sleep quality and duration As measured by questions measuring personal satisfaction with sleep quality and duration

Items measuring circadian rhythm variables e.g. Zeitgebers

Cognitive functioning will be measured with a battery of computerized neuropsychological tests.

Cognitive functioning will be measured with a battery of non-computerized neuropsychological tests.

Demographic data are documented in the hospital records.