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Completed

NCT Number: NCT05826951

Social Effects of Alcohol

In this study the investigator will assess the effect of a moderate dose of alcohol on emotional responses and feelings of connection during a dyadic semi-structured social interaction

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Key information

Conditions

Alcohol Drinking Behavior Drinking Behavior

Age range

21 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

University of Chicago

Chicago, Illinois, 60637, United States

About this study

The study will use a within-subject crossover design with four sessions, in which participants receive alcohol or placebo across sessions. During the four sessions, the participants will engage in a conversation with a stranger, and emotional responses and feelings of connection will be assessed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • non-problem alcohol consumption of 2-20 drinks per week
  • high school diploma or equivalent
  • BMI between 19 and 26
  • verbal fluency in English

Exclusion criteria

  • High blood pressure
  • Any medical condition requiring regular medication
  • Individuals with a current (within the last year) DSM-IV Axis 1 diagnosis
  • Women who are pregnant or trying to become pregnant.

Treatment and study plan

Alcohol

Drug

Alcohol (0.8g/kg)

Placebo

Drug

Placebo

Primary outcomes

  1. facial emotional responses

    Time frame: during the length of the conversation (45 min)

    alterations in the rate of positive facial expressions during the conversation, measured by muscle action units. These will be compared between the drug and placebo sessions

  2. self-reported feelings of connection

    Time frame: at the end of each session (3.5 hrs post-drug administration). Changes across sessions will be assessed

    self-other overlap measure ratings 1-7, greater ratings indicates greater feelings of connection

Interested in participating?

Completed

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Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Collaborators

  • National Institute on Drug Abuse (NIDA)
  • National Institutes of Health (NIH)

Registry information

Acronym: SEA

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Apr 24, 2023
Registry last updated
Jan 24, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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