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Completed

NCT Number: NCT05809726

The Effects of Manual Lymphatic Drainage on the Autonomic Nerve System

Forty healthy women who met the inclusion criteria were included in the study. In the single-blind randomized controlled study, the participants were divided into 3 groups manual lymphatic drainage(MLD), sham MLD, and control group. After evaluating the demographic information, blood pressure, and heart rate variability (HRV) of the participants, the cold pressure test was applied. Immediately after the test, blood pressure and HRV were re-evaluated. The MLD group received short neck, abdominal, and lymph node stimulation and right arm MLD applications. A sham protocol was applied to the sham MLD group. The control group was asked to lie on their back for 10 minutes. After the application, blood pressure and HRV were re-evaluated.

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Key information

Conditions

Healthy

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Kutahya Health Sciences University

Kütahya, 43100, Turkey (Türkiye)

About this study

The participants included in the study were randomly divided into 3 groups; manual lymph drainage, sham manual lymph drainage, and a control group in the computer program.

Participants rested for 5 minutes before the first evaluation. The first evaluation was made after the demographic information of the participant was obtained. Within the scope of this evaluation, blood pressure, heart rate, and heart rate variability were evaluated. All assessments were performed on the patient's dominant upper extremity. After the evaluation, cold pressure test was applied to the dominant extremity. A second assessment was made immediately after the test. All of the parameters examined within the scope of the first evaluation were examined for the second time. Appropriate treatment was applied to the group to which the participant belonged. After the treatment, the third evaluation was made and the study was terminated. All participants were asked to avoid exercise, caffeine, energy drinks, and heavy meals at least 1 hour before the test. Environmental noise, light, and temperature were controlled during the test.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • being over 18 years of age
  • being voluntary to participate in the study

Exclusion criteria

  • having advanced cardiorespiratory diseases
  • orthopedic and neurological problems
  • using medication related to pain
  • cardiovascular system, having skin disorders that prevent skin contact
  • having cold urticaria

Treatment and study plan

Manual Lymph Drainage

Other

one session 20 minutes

Other names: Sham manual lymph drainage

Primary outcomes

  1. autonomic functions assessment

    Time frame: 1 year

    heart rate variability

  2. physiological parameter

    Time frame: 1 year

    Systolic blood pressure (mmHg) and diastolic blood pressure (mmHg)

Sponsors and collaborators

Lead sponsor

Kutahya Health Sciences University

Other

Registry information

Official study title

Does Manual Lymph Drainage Affect Autonomic Functions in Healthy Women?

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Apr 12, 2023
Registry last updated
Apr 12, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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