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OpenTrials
Completed

NCT Number: NCT05729841

Study of Ocean Rowing Muscle Metabolism. 1. What Effect Does Rowing 3000 Miles Across Atlantic Ocean Have on Calf Muscle Size? 2. In the Catabolic State of Extreme Endurance, is Muscle Loss Uniform or Can the Human Body Select Depending on Load and Nutrient Availability?

Little is known on the human adaptation to extreme endurance and with the increasing popularity in long duration events we seek to provide insight into the physiological and metabolic adaptation processes of ocean rowing.

Rowing 12-18 hours a day will illicit a high energy expenditure and anecdotally people have lost large amounts of body weight and variable amounts of muscle mass, particularly in the lower limbs. This may provide insights and a potential new model to to study muscle unloading.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Exeter

Exeter, Devon, EX2 4TH, United Kingdom

About this study

Previous research has investigated factors determining muscle loss through bed rest and limb immobilisation. These methods are limited in that some do not include inflammation or changes in nutrition, which have been shown to be key drivers of muscle loss. These studies aim to investigate a potentially new model of muscle unloading.

Ocean rowing is an ultra-endurance sport where people spend 35-90 days at sea. Usually rowing for a minimum of 12 hours a day, in a 2-hour on/off shift pattern with daily food rations. Rowers lose body and muscle mass. There is likely to be low-grade inflammation, nutritional deficit, fatigue and rowers do not stand up for the entire crossing. Part 1 aims to quantify this muscle loss by inviting rowers in the annual 3000 mile Talisker Whisky Atlantic Challenge 2020 to take part. While part 2 aims to continue the work by measuring upper and core muscles as well as lower limb muscles from the first study with the aim of understanding how the body allocates resources in a hypocaloric, high energy expenditure environment.

Muscle mass of the lower limbs of the rowers will be measured with ultrasound, as well as body mass, body composition, energy expenditure and nutritional intake, the week before the race and immediately after arrival in Antigua. As well as adding novel insights to the knowledge base around factors affecting ultra endurance performance, the results will then be used to inform future intervention studies aimed at preventing muscle loss.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Taking part in the Talisker Whisky Atlantic Challenge 2020 and 2021

Exclusion criteria

  • lower limb amputee musculoskeletal, metabolic, neurological disease pacemaker fitted

Treatment and study plan

Ocean row

Other

the Talisker Whisky Atlantic Challenge annual ocean rowing race.

Primary outcomes

  1. Energy Expenditure

    Time frame: 5-7 days in final week of row

    Amount of kcals expended per day

  2. Calf Muscle thickness

    Time frame: 5-7 weeks

    Pre - Post measurements of calf muscle thickness

  3. Energy Intake

    Time frame: 5-7 days in final week of row

    Amount of kcals consumed per day

Secondary outcomes

  1. Difference in rate of muscle thickness loss between males and females

    Time frame: 5-7 weeks

    Absolute and relative differences in energy balance, body mass loss or muscle loss

  2. Difference in rate of muscle thickness loss in older vs younger rowers

    Time frame: 5-7 weeks

    Are there any age-related differences in energy balance, body mass loss or muscle loss

Sponsors and collaborators

Lead sponsor

University of Exeter

Other

Registry information

Official study title

StORMM 1:What Effect Does Rowing 3000 Miles Across Atlantic Ocean Have on Calf Muscle Size? StORMM 2. In the Catabolic State of Extreme Endurance, is Muscle Loss Uniform or Can the Human Body Select Depending on Load and Nutrient Availability?

Acronym: StORMM

Important dates

Study start
2020
Primary completion
2022
Study completion
2024
First posted
Feb 15, 2023
Registry last updated
May 21, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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