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Completed

NCT Number: NCT05702047

Comparing Nose & Mouth Breathing During Exercise

The purpose of this study is to compare physiological responses in cardiovascular variables between nose and mouth breathing at rest and during exercise.

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Key information

Conditions

Healthy

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Florida State University

Tallahassee, Florida, 32306, United States

About this study

Breathing patterns can affect the cardiovascular system. Little is known about how nose versus mouth breathing affects cardiovascular variables (blood pressure, heart rate, etc.) at rest and during exercise. It has been suggested that breathing through the nose can cause calmness and lower blood pressure. However, research is needed to examine the extent to which breathing through the nose affects cardiovascular variables at rest and during exercise. Therefore, we will compare cardiovascular variables between nose-only and mouth-only breathing. The rate of breathing will be fixed (using an audible metronome) for both breathing conditions (nose-only vs mouth-only) based on an individual's free breathing (i.e., no breathing cues) breathing rate.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Body mass index: ≤30 kg/m2
  • Resting Blood pressure: ≤140/90 mmHg

Exclusion criteria

  • Overt cardiovascular (e.g., diagnosed hypertension), respiratory, neurological, renal, liver, and/or metabolic health condition
  • Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes)

Treatment and study plan

Nose-only breathing

Behavioral

Participants will breathe only through their nose (mouth closed) during rest and submaximal exercise.

Mouth-only breathing

Behavioral

Participants will breathe only through their mouth (nose clips prevent nose breathing) during rest and submaximal exercise.

Primary outcomes

  1. Blood Pressure During Exercise Between Study Arms

    Time frame: Up to one day

    Systolic blood pressure will be measured in the laboratory during submaximal exercise with nose-only breathing and mouth-only breathing.

  2. Heart Rate During Exercise Between Study Arms

    Time frame: Up to one day

    Heart rate will be measured in the laboratory during submaximal exercise with nose-only breathing and mouth-only breathing.

Secondary outcomes

  1. Rating of Perceived Exertion During Exercise Between Study Arms

    Time frame: Up to one day

    Participants will report their rating of perceived exertion (numerical scores of 6-20, with 20 being the greatest exertion) based on a validated scale during submaximal exercise with nose-only breathing and mouth-only breathing.

  2. Rating of Perceived Breathlessness During Exercise Between Study Arms

    Time frame: Up to one day

    Participants will report their rating of perceived breathlessness (numerical scores of 0-10, with 10 being the greatest breathlessness) based on a validated scale during submaximal exercise with nose-only breathing and mouth-only breathing.

Sponsors and collaborators

Lead sponsor

Florida State University

Other

Registry information

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jan 27, 2023
Registry last updated
Nov 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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