Skip to main content
OpenTrials
Completed

NCT Number: NCT05556213

The Relation Between MiR-125b-5p and Staging of Endometriosis

78 endometriosis patients presented with infertility were clinically examined and the diagnosis was assured by US imaging. The study also included 11 control fertile women free of gynecological problems as a control for lab tests. Patients and controls gave blood samples for lab investigations. All patients underwent diagnostic abdominal laparoscopy under general anesthesia for disease staging. Quantitative determination of expression levels of genes of microRNA-125b-5p and 203a was conducted using qRT-PCR.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Endometriosis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Urogenital Diseases

Age range

22 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Tanta university

Tanta, El-Gharbyia, 13511, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who presented clinical pictures suggestive of EM disease

Exclusion criteria

  • Patients with previous pelvic or abdominal surgery that may hinder the laparoscopic examination,
  • patients who were suspicious of having malignancy elsewhere in the body region,
  • pregnant women,
  • patients who had diabetes mellitus,
  • body mass index (BMI) of >30 kg/m2, coagulopathies, and autoimmune disorders.

Treatment and study plan

laparoscopic examination

Procedure

laparoscopic examination for staging of endometriosis

Blood sampling

Diagnostic Test

Blood sample to detect endometriosis

Primary outcomes

  1. Validity of Plasma expression level

    Time frame: two weeks

    the diagnostic validity of estimation of plasma expression levels of MiR-125b-5p and 203a for diagnosis and staging of endometriosis.

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Estimation of Plasma Levels of MicroRNA 125b-5p and Transvaginal Ultrasonography May Spare Laparoscopy for Staging of Endometriosis

Important dates

Study start
2020
Primary completion
2022
Study completion
2022
First posted
Sep 27, 2022
Registry last updated
Sep 27, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.