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OpenTrials
Active, not recruiting

NCT Number: NCT05537701

Tissue Eosinophils in Non-Small Cell Lung Cancer (the TEN Study)

The primary objective is to describe eosinophil infiltration in resected (early stage) NSCLC.

Secondary objectives are:

* to investigate the correlation of T-Eos and B-Eos in the aforementioned patient population; * to investigate the correlation between T-Eos and overall & disease-free survival; * to investigate the localization of T-Eos (periphery vs. center of the tumor lesions).

Active, not recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Non-small Cell Lung Cancer Bronchial Neoplasms Carcinoma, Bronchogenic Carcinoma, Non-Small-Cell Lung Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de Liege

Liège, 4000, Belgium

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Resected, early stage NSCLC between 01-01-2015 and 30-04-2022 with available tumour tissue

Exclusion criteria

  • Inclusion in a clinical study contraindicating enrollment in the present study

Treatment and study plan

Primary outcomes

  1. Percentage of tumor associated tissue eosinophilia by immunohistochemistry and computerised quantification

    Time frame: October 2022

Secondary outcomes

  1. to investigate the correlation of tissue (T)-Eos and blood (B)-Eos in the aforementioned patient population

    Time frame: December 2022

    Tissue and blood eosinophil correlation

  2. to investigate the correlation between T-Eos and overall & disease-free survival

    Time frame: December 2022

    overall and disease-free survival

  3. to investigate the localization of T-Eos (periphery vs. center of the tumor lesions)

    Time frame: December 2022

    tissue eosinophil localisation

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Liege

Other

Registry information

Acronym: TEN

Important dates

Study start
2022
Primary completion
2027
Study completion
2027
First posted
Sep 13, 2022
Registry last updated
Jan 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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