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Completed

NCT Number: NCT05382520

Sensory Rehabilitation in Chemotherapy Induced Peripheral Neuropathy (CIPN)

Physiotherapist research about Sensory rehabilitation in chemotherapy induced peripheral neuropathy (CIPN) with the aid of questioners and physiotherapy practice

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Key information

Conditions

CIPN Nervous System Diseases Neuralgia Neurologic Manifestations Neuromuscular Diseases Pain Pathological Conditions, Signs and Symptoms Peripheral Nervous System Diseases Signs and Symptoms

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Shamir medical center

Beer Yaaqov, Israel

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18 and over who suffer from chemotherapy-induced neuropathy (CIPN), according to the patient's report, more than 3 months since the end of the chemotherapy treatment.

Exclusion criteria

  • Sensory damage / neuropathy that existed even before the start of chemotherapy
  • Incidents of recurrent falls even before the start of chemotherapy (over 2 falls for 6 months)
  • Central nervous system involvement
  • Major pre-morbid orthopedic lower limb impairment
  • Hebrew language not sufficient for assessment and treatment

Treatment and study plan

Questionares and practice

Diagnostic Test

Questionares and practice

Primary outcomes

  1. TNAS

    Time frame: 2 years

    TNAS -Treatment-Induced Neuropathy Assessment Scale. 0-90. higher score = worse status

  2. VAS

    Time frame: 2 years

    0-100 mm visual scale: self-reporting pain assessment from no pain to worst pain possible. We will ask for current pain and the worst pain during the last week.

  3. FABS

    Time frame: 2 years

    Fullerton Advanced Balance Scale: high function balance test - consisting of 10 activities in both static and dynamic phases; 10-40, higher scores are better.

  4. TUG

    Time frame: 2 years

    Timed Up and Go: fall prediction screening test; measures time taken to raise from a chair walking 3 meters and re-sit.

  5. NSA

    Time frame: 2 years

    Nottingham Sensory Assessment: sensory detection and discrimination test

  6. Semmes-Weinstein monofilament testing

    Time frame: 2 years

    tactile detection threshold

  7. LEPT

    Time frame: 2 years

    Lower Extremity Position Test: proprioception detection and quantification

  8. Allodynia

    Time frame: 2 years

    tested by non-painful mechanical stimulation: gentle brushing and monofilament

Sponsors and collaborators

Lead sponsor

Assaf-Harofeh Medical Center

Other Gov

Collaborators

  • Zefat Academic College

Registry information

Important dates

Study start
2022
Primary completion
2024
Study completion
2025
First posted
May 19, 2022
Registry last updated
Sep 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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