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OpenTrials
Completed

NCT Number: NCT04961112

Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits

This study investigates the potential of cranial electrotherapy stimulation to mitigate anxiety induced cognitive deficits

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Key information

Conditions

Anxiety Anxiety Disorders Cognition Disorders Cognitive Deficit Mental Disorders Neurocognitive Disorders

Age range

18 year–28 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tufts University

Medford, Massachusetts, 02155, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between 18-28 years old

Exclusion criteria

  • History of diagnosis with a neurological or psychiatric disorder.

Treatment and study plan

Cranial Electrotherapy Stimulation

Device

Participants will receive cranial electrotherapy stimulation stimulation on one of two separate visits (within-subjects).

Other names: Transcranial Pulsed Current Stimulation, Cranial Electrical Stimulation

Sham Cranial Electrotherapy Stimulation

Device

Participants will receive sham stimulation on one of two separate visits (within-subjects).

Primary outcomes

  1. Task switching

    Time frame: 68 weeks

    Switch cost (mean switch reaction time- mean stay reaction time)

  2. Working memory (N-back)

    Time frame: 68 weeks

    2-back condition mean accuracy

  3. Inhibition (Stroop)

    Time frame: 68 weeks

    Stroop interference cost (mean incongruent reaction time- mean congruent reaction time)

  4. Processing speed (Simple reaction time task)

    Time frame: 68 weeks

    Mean reaction time

Interested in participating?

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Sponsors and collaborators

Lead sponsor

Tufts University

Other

Registry information

Important dates

Study start
2021
Primary completion
2025
Study completion
2025
First posted
Jul 14, 2021
Registry last updated
Apr 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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