Exploring Breathing Patterns

Study Title Exploring patterns of speech and breathing to indicate the presence of obstructive respiratory disease.

Study Design Prospective Case Control Study Study Participants Participants will be patients attending the respiratory physiology clinic at the Cardiopulmonary Unit, Prince Charles Hospital for an assessment of their lung function. In addition a cohort of control participants without obstructive respiratory disease will be recruited with the assistance of the British Lung Foundation charity.

Planned Size of Sample (if applicable) We have received funding for 52 ½ day sessions and we plan to recruit on average 2 participants per session. As such we aim to recruit a minimum of 100 participants. In addition we are working with the British Lung Foundation to recruit a smaller Cohort of control participants and aim to recruit a minimum of 25 control participants.

Planned Study Period Jan 2019 - Aug 2019 Research Aim(s) This primary objective of this novel study it to create an anonymised database of speech patterns of patients with chronic respiratory disease and healthy aged matched controls for comparison with lung function and medical history.

The primary aims are to:

* Collect breathing patterns from individuals under a range of talking modalities * Understand how easy it is to gather short speech recordings * Explore the preferences of patients to be recorded talking

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Key information

Conditions

COPD Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Cwm Taf Morgannwg Health Board

Abercynon, Wales, CF45 4SN, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

6.1.2 Inclusion criteria Patient Participants

Adult patient >18 years old referred for spirometry in the Respiratory Physiology Clinic at Prince Charles Hospital;
Clinically defined obstructive or restrictive respiratory disease (indicated by spirometry)
Clinically stable (indicated by being able to undergo spirometry)
No significant unstable disease co-morbidities (indicated by being able to undergo spirometry)
Capable of providing informed consent.
Willing to take part in all study measurements.
The speaking exercise will be conducted in English on this study.
Participants are not taking part in any other research. 6.1.3 Inclusion criteria Control Participants

No obstructive or restrictive respiratory disease (indicated by spirometry) 2. Clinically stable (indicated by being able to undergo spirometry) 3. No significant unstable disease co-morbidity's (indicated by being able to undergo spirometry) 4. Capable of providing informed consent. 5. Willing to take part in all study measurements. 6. The speaking exercise will be conducted in English on this study. 7. Participants are not taking part in any other research.

6.1.4 Exclusion criteria for both Patient and Control Participants

Any form of challenge testing in the Respiratory Physiology Department involving salbutamol.
Severe Sensory and/or Cognitive Impairment
Inability to complete study measurements

Treatment and study plan

Speech Recognition

Diagnostic Test

Speech Recognition

Primary outcomes

Collect breathing patterns from individuals under a range of talking modalities

Time frame: less than 5 minutes

breathing pattern
Understand how easy it is to gather short speech recordings

Time frame: 3 minutes

verbal description
Explore the preferences of patients to be recorded talking

Time frame: 3 minutes

verbal description

Sponsors and collaborators

Lead sponsor

Cwm Taf University Health Board (NHS)

Other Gov

Registry information

Official study title

Exploring Patterns of Speech and Breathing to Indicate the Presence of Obstructive Disease

Acronym: EPISODE

Important dates

Study start: 2019
Primary completion: 2026
Study completion: 2026
First posted: Feb 15, 2021
Registry last updated: Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed