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NCT Number: NCT04433676

Early PONV - a Registry Based Study in Sweden.

The study is an registry study based on data from the Swedish Perioperative Registry (SPOR) during the years 2016-2022 with the aim to explore the risk for postoperative nausea and vomiting at the recovery unit (early PONV). The study will explore several cohorts (for example a specific procedure) on a national basis, report the risk for early PONV and identify associated factors.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Västernorrland County Council / Sundsvall Hospital

Sundsvall, X, 851 86, Sweden

Location status: Recruiting

Location contact

Antonio Moraitis, M.D. Ph.D.

CONTACT

[email protected]

Antonio Moraitis, MD

SUB_INVESTIGATOR

Helena Nyström, MD PhD

SUB_INVESTIGATOR

Jakob Wallden, M.D. PhD.

CONTACT

[email protected]

+46703644392

Jakob Wallden, MD PhD

PRINCIPAL_INVESTIGATOR

Jenny Jonsson

SUB_INVESTIGATOR

Magnus Hultin, MD PhD

SUB_INVESTIGATOR

About this study

The study is a registry study based on data from the Swedish Perioperative Registry (SPOR) during the years 2016-2022 with the aim to explore the risk for postoperative nausea and vomiting at the recovery unit (early PONV).

Almost all hospitals in Sweden report surgical procedures to SPOR and for the years 2016-2019 there are almost 1.7 million procedures in the registry for patients >18years. Data will be extracted from SPOR on a yearly basis and results will be reported on selected cohorts (time periods and/or type of surgical procedure) during the study period.

There is an option for hospitals to register nausea and vomiting occurring at the recovery unit and submit the data to SPOR. If a hospital choose to use the variable in their dataset, all patients at their unit needs to be registered either with [No_Nausea or Vomiting], [Nausea] or [Nausea or Vomiting]. In the year 2019, more than 50% of procedures under anesthesia in the registry had registration of PONV. The strength with this system is that if a unit uses the variable, all cases will be classified either as "noPONV" or "PONV".

The investigators aim to use the variable PONV at the recovery unit to describe the risk for early PONV and explore associated factors in several cohorts of surgical procedures in Sweden.

The first dataset (2016-2018) was sent to the investigators from the SPOR registry in May 2019 and during the period June 2019- May 2020, the dataset was used to build up a model for the analysis of data with a preliminary report of elective surgeries in Sweden the year 2017.

An updated dataset (all cases 2016-2025) was retrieved from SPOR in June 2026 and further analysis and reporting is based on the most updated dataset (yearly basis until 2029).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Procedure under general or regional anaesthesia
  • Age >=18 years at the day of the procedure.

Exclusion criteria

  • No entry of the PONV-variable in the SPOR-registry

Treatment and study plan

No intervention

Other

Primary outcomes

  1. PONV

    Time frame: At the recovery unit, up to 24 hours after surgery.

    Nausea or Vomiting

Study contacts

Contact information is provided by the study sponsor or research team.

Jakob Wallden, MD PhD

CONTACT

[email protected]

0046703644392

Sponsors and collaborators

Lead sponsor

Jakob Wallden

Other Gov

Collaborators

  • Umeå University

Registry information

Official study title

Risk of Early Postoperative Nausea and Vomiting (PONV) - a Study With Data From the Swedish Perioperative Register (SPOR).

Acronym: SPOR-PONV

Important dates

Study start
2016
Primary completion
2029
Study completion
2029
First posted
Jun 16, 2020
Registry last updated
Aug 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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