Procyanidin B2 Enriched Cocoa Effects on Mitochondrial Biogenesis

The purpose of this study is to test how cocoa-rich procyanidin B2 affect the mitochondrial exercise adaptations.

Completed

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Key information

Conditions

Athletes

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidad Europea de Madrid

Villaviciosa de Odón, Madrid, 28670, Spain

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Men/Women
Age between 18 and 45 years
Aerobic power of oxygen consumption greater than or equal to 55 mL / kg / min

Exclusion criteria

Smoke
Any chronic disease
Intake of nutritional or ergogenic supplements
Chronic medication
Cocoa allergy

Treatment and study plan

procyanidin B2 enriched cocoa

Dietary Supplement

Volunteers will intake 5 grams per day of dietary supplement for 10 weeks

Primary outcomes

Difference in mitochondrial number

Time frame: 10 weeks

Number of mitochondria in blood cells measured by qPCR using mitochondrial COX1 gene and beta globin as housekeeping nuclear gene
Difference in exercise performance

Time frame: 10 weeks
Maximum oxygen consumption
- of incomplete pulmonary gas exchange on VO2 max - Powers - Citado por 318
- determination of cardiorespiratory fitness and training … - Clark - Citado por 180 Maximum oxygen consumption

Interested in participating?

Completed

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Sponsors and collaborators

Lead sponsor

Universidad Europea de Madrid

Other

Registry information

Acronym: PROMETHEO

Important dates

Study start: 2020
Primary completion: 2020
Study completion: 2020
First posted: Mar 10, 2020
Registry last updated: Nov 4, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed