The Role of Netrin -1 in Acute Coronary Syndrome

In our study, Netrin -1; We found that patients with ACS increased at the time of admission, decreased TIMI 3 flow after angiography, and higher risk groups in high risk groups such as TIMI and GRACE were found to have higher Netrin-1 levels.

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Key information

Conditions

Acute Coronary Syndrome Cardiovascular Diseases Heart Diseases Myocardial Ischemia Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients over the age of 18
diagnose ACS
patients undergoing angiography

Exclusion criteria

CVE history
Neurological disease
Pregnancy and Lactation
Liver failure
Diagnosed malignity
Use of anticonvulsant and nephrotoxic medication
Chronic kidney disease
Not having angiography
Developing acute renal failure after angiography
Patients who rejected to participate were excluded.

Treatment and study plan

netrin-1 value on admission to hospital

Other

Primary outcomes

serum netrin-1 value

Time frame: 30 minute

Netrin-1 in plasma was measured by enzyme-linked immunosorbent assay (ELISA) (Mybıosource MBS044526 ) All assays were performed in duplicate. Plasma Netrin-1 is expressed in picograms (pg) per mg.

Sponsors and collaborators

Lead sponsor

Aksaray University Training and Research Hospital

Other

Registry information

Official study title

The Effect of Serum Netrin-1 Levels on Diagnosis and Prognosis in Patients Presenting to the Emergency Department With Acute Coronary Syndrome

Acronym: ACS-NETRİN-1

Important dates

Study start: 2013
Primary completion: 2014
Study completion: 2018
First posted: Jul 19, 2019
Registry last updated: Jul 19, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed