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Completed

NCT Number: NCT03850925

Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars

This study compares the application of a picosecond 1064-nm laser with a diffractive lens array with nonablative fractional laser for the treatment of acne scarring.

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Key information

Conditions

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dongtan Sacred Heart Hospital, Hallym Universtiy College of Medicine

Hwaseong-si, Gyeonggi-do, 18450, South Korea

About this study

This trial is a 17-week, prospective, randomized split-face study that compares the results between two facial sides either receiving the picosecond 1064-nm laser or nonablative fractional laser treatment for atrophic acne scar.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects with facial atrophic acne scars
  • Subjects who observe the schedules and protocols of the clinical trial
  • Subjects who give informed consent to participate in the clinical trial

Exclusion criteria

  • Subjects who have active acne under treatment
  • Subjects who had received any other treatments for acne scarring for 6 months prior to the first treatment
  • Subjects who underwent other treatments including chemical, mechanical or laser resurfacing during the study period
  • Subjects who have current acute illness
  • Subjects who are considered inappropriate for the clinical trial under the judgement of investigators

Treatment and study plan

laser therapy

Procedure

4 consecutive sessions of laser therapy

Primary outcomes

  1. Changes in the mean of the ECCA grading scale

    Time frame: Week 17

    The ECCA (échelle d'évaluation clinique des cicatrices d'acné) grading scale: minimum score 0; maximum score 270; higher values represent a worse outcome.

Sponsors and collaborators

Lead sponsor

Dongtan Sacred Heart Hospital

Other

Registry information

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Feb 22, 2019
Registry last updated
Aug 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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