Hemostasis Achievement Reflecting Inflammatory Status of the Pulp Based on Cytokine Levels: A Cohort Study.

The possibility has been raised of diagnosing pulpal pathological status using the cytokines that are released during the inflammation process in healthy as well as infected tooth pulp. Cytokines are small polypeptides secreted by leucocytes and other inflammatory cells and are known to play important roles in the intensity and duration of the immune response

Inclusion criteria

• healthy children
• patients had not used any inflammatory medications
• primary molar teeth of these children were included based on the following clinical and radiographic criteria:

• no clinical symptoms or evidence of pulp degeneration (pain on percussion, history of swelling or sinus tract
• no spontaneous pain
• no radiographic signs of internal or external resorption, widened periodontal ligament space, or furcal/periapical radiolucency
• physiological root resorption of no more than one third the root length
• a deep caries lesion with a likelihood of pulp exposure during caries removal

Exclusion criteria

• patients used any anti-inflammatory medication