Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of type 2 diabetes (T2D) is heavily debated but evidence from large populations in China is scant. The investigators aim to use data from the China Health and Nutrition Survey (CHNS) to assess the long-term association between fish, PUFA intake and T2D risk.

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Key information

Conditions

Type2 Diabetes

Age range

20 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of T2D is heavily debated but evidence from large populations in China is still lacking. The investigators aim to utilize data from China Health and Nutrition Survey (CHNS, 1997-2011). The investigators will calculate cumulative means of fish and PUFA intake based on 3-day food records in each wave. Sex-specific Cox regression models will be used to estimate relative risk of T2D. Results from this work will provide epidemiological evidence for improving recommendations on fish and PUFA intake for Chinese in dietary guidelines.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults aged ≥20 with complete data on diet and follow-up time

Exclusion criteria

Missing information for Type 2 diabetes
Type 2 diabetes
Cardiovascular disease

Treatment and study plan

Primary outcomes

Type 2 diabetes

Time frame: From entry into the study (baseline: 1997-2009) until 2011

Incidence of type 2 diabetes, on basis of self-reported physician diagnosis, fasting plasma glucose ≥ 7.0 mmol/l or HbA1c ≥ 6.5%

Secondary outcomes

Fish and polyunsaturated fatty acids intake

Time frame: From entry into the study (baseline: 1997-2009) until 2011

Cumulative averages of fish and PUFA intake based on 3-day 24-hr recall in each wave

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Sponsors and collaborators

Lead sponsor

Zhejiang University

Other

Collaborators

National Institute of Health and Nutrition

Registry information

Official study title

Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes in CHNS

Important dates

Study start: 1989
Primary completion: 2011
Study completion: 2012
First posted: Aug 23, 2017
Registry last updated: Mar 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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