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OpenTrials
Completed

NCT Number: NCT03102983

Sensory-motor Interactions in the Perception of Vowels: a Study in Repetition - Suppression

The aim of our study is to show by fMRI the involvement of the motor system in the perception of speech, and more particularly how this implication is modulated by the degree of prototypicity of the stimuli.

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Key information

Conditions

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU Grenoble-Alpes

Grenoble, Isère, 38043, France

About this study

Each participant will undergo two visits:

Phase 1: The Gipsa-Lab Laboratory's Department of Speech and Cognition. This first visit will make it possible to make recordings of their vowel productions and to verify that the participants correspond to the criteria necessary for the study (passing the Edinburgh manual laterality test and auditory thresholds checked using a " An audiogram). It will also be an opportunity to provide them with the consent documents and the fact sheet, which will give them time to read it before the MRI exam. The duration of this first visit will be approximately 1 hour.

Phase 2: fMRI review in the 3Tesla MRI Unit at the Grenoble University Hospital Center. Participants will first undergo a medical examination in order to verify their absence of contraindication to the MRI examination. At the end of this medical examination, the consent of participation will be signed. The participants will then be able to carry out the MRI examination for a duration of about 1h15, then the behavioral judgment test of perceptual distance. The total duration of this second visit will be approximately 1h45.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Medicall exam before MRI
  • Pregnant Women
  • Patients aged 18-45 years, Right-handed
  • without neurologic and/or psychiatric troubles
  • normal audition
  • Audition normale
  • French mother tongue
  • Social security affiliation

Exclusion criteria

  • protected person
  • MRI contraindication
  • claustrophobia
  • respirtaory and cardiovascular pathology
  • toxic substances taking

Treatment and study plan

MRI functional

Other

vowels records and MRI session

Primary outcomes

  1. Evaluate the involvement of the speech motor system in the perception of vowels, using functional magnetic resonance imaging (fMRI).

    Time frame: One hour and forty five minutes

    fMRI measured

Sponsors and collaborators

Lead sponsor

University Hospital, Grenoble

Other

Collaborators

  • GIPSA-LAB

Registry information

Acronym: NEUROPHONE

Important dates

Study start
2016
Primary completion
2016
Study completion
2017
First posted
Apr 6, 2017
Registry last updated
Oct 10, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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