The Effects of Secondary Smoking During One Lung Ventilation

Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking. The aim of study is to predict the incidence of hypoxemia and airway damage during one lung ventilation for lobectomy.

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Key information

Conditions

Smoking Behavior Hypoxia Oxygen Deficiencies Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Respiratory

Study type

Interventional

Phase

Not applicable

About this study

Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube will be included in this study. These patients will be divided into 2 groups. Groups S which will be included non smoking and secondary smoking and group SS which will be included secondary smoking ( smoking near him more than 10 cigarettes per day fore more than 5 years). Intra and postoperative arterial oxygen tension, arterial carbon dioxide tension and intraoperative peak airway pressure will be compared between the two groups.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.

Exclusion criteria

Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.

Treatment and study plan

One Lung Ventilation

Other

Primary outcomes

arterial oxygen tension

Time frame: From beginning of Anesthesia to 1st day of surgery
arterial carbon dioxide tension

Time frame: From beginning of Anesthesia to 1st day of surgery
intraoperative peak airway pressure

Time frame: during intraoperative ventilation

Sponsors and collaborators

Lead sponsor

Inonu University

Other

Registry information

Official study title

The Effects of Secondary Smoking to Intraoperative Arterial Oxygen Tension During One Lung Ventilation in Lobectomy

Important dates

Study start: 2016
Primary completion: 2017
Study completion: 2017
First posted: Dec 30, 2016
Registry last updated: Apr 5, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed